The Synthesis and Applications of 1-Bromo-2,3-difluorobenzene: A Comprehensive Overview
In the realm of fine chemicals, certain molecules serve as indispensable linchpins for a multitude of advanced applications. 1-Bromo-2,3-difluorobenzene, identified by its CAS number 38573-88-5, is one such compound. This halogenated aromatic hydrocarbon, with the molecular formula C6H3BrF2, is a critical intermediate, primarily sought after for its utility in the synthesis of pharmaceuticals and other complex organic molecules. Its unique structural arrangement of fluorine and bromine atoms on a benzene ring confers specific reactivity patterns that are highly valued in modern chemical synthesis.
The chemical profile of 1-Bromo-2,3-difluorobenzene is characterized by its liquid state at room temperature, a relatively high boiling point of 234°C, and a density of approximately 1.724 g/mL. These physical properties, coupled with its high purity (often exceeding 98%), make it amenable to various synthetic transformations. The presence of two fluorine atoms adjacent to the bromine atom enhances its utility in regioselective reactions. It is frequently employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, to form new carbon-carbon bonds, and in Buchwald-Hartwig amination to create carbon-nitrogen bonds. These reactions are fundamental to building the complex molecular architectures required for Active Pharmaceutical Ingredients (APIs) and other specialty chemicals.
Ningbo Inno Pharmchem Co., Ltd. is a dedicated supplier of high-quality 1-Bromo-2,3-difluorobenzene, recognizing its pivotal role in the chemical supply chain. We ensure that our product meets the stringent purity requirements demanded by pharmaceutical and fine chemical industries. The compound's utility extends beyond pharmaceuticals; it is also a valuable intermediate in the development of agrochemicals and advanced materials. The ability to precisely introduce fluorinated moieties into organic molecules is a significant advantage in achieving desired biological activity or material properties, making 1-bromo-2,3-difluorobenzene a compound of consistent demand.
The synthesis and application of 1-Bromo-2,3-difluorobenzene are central to enabling innovation in various scientific fields. Its role in creating drugs like RIMEGEPANT SULFATE for migraine treatment highlights its direct impact on healthcare. Furthermore, its utility as a general organic synthesis intermediate means it is a frequently searched term for chemists looking to buy reliable chemical building blocks. Proper storage, typically in a cool, dry, and well-ventilated environment, is essential to maintain the compound's integrity and reactivity for optimal results in synthesis. Ningbo Inno Pharmchem Co., Ltd. is committed to providing not just the chemical itself, but also the support needed for its effective use.
In essence, 1-Bromo-2,3-difluorobenzene (CAS 38573-88-5) is a versatile and essential intermediate that underpins progress in pharmaceutical synthesis, agrochemical development, and materials science. Its reliable supply and high quality, as provided by Ningbo Inno Pharmchem Co., Ltd., empower researchers and manufacturers to push the boundaries of chemical innovation.
Perspectives & Insights
Alpha Spark Labs
“Proper storage, typically in a cool, dry, and well-ventilated environment, is essential to maintain the compound's integrity and reactivity for optimal results in synthesis.”
Future Pioneer 88
“is committed to providing not just the chemical itself, but also the support needed for its effective use.”
Core Explorer Pro
“In essence, 1-Bromo-2,3-difluorobenzene (CAS 38573-88-5) is a versatile and essential intermediate that underpins progress in pharmaceutical synthesis, agrochemical development, and materials science.”