At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to advancing chemical synthesis through the provision of high-quality building blocks. Boc-Asn(Trt)-OH, chemically known as N-alpha-Boc-N-gamma-trityl-L-asparagine (CAS 132388-68-2), is a prime example of such a critical intermediate. Its synthesis and application are fundamental to achieving success in various areas of chemical research, particularly in peptide synthesis.

The synthesis of Boc-Asn(Trt)-OH involves protecting the alpha-amino group of L-asparagine with a tert-butyloxycarbonyl (Boc) group and the side-chain amide nitrogen with a trityl (Trt) group. This dual protection strategy is essential for its role in Solid-Phase Peptide Synthesis (SPPS). The Boc group allows for selective deprotection under mild acidic conditions, enabling peptide chain elongation, while the Trt group offers robust protection for the asparagine side chain. The trityl group's steric bulk is key to its function, not only in preventing aspartimide formation but also in enhancing the solubility of the amino acid derivative in organic solvents commonly used in SPPS. This improved solubility directly contributes to higher reaction efficiency and purer peptide products.

The applications of Boc-Asn(Trt)-OH are diverse, spanning from the production of therapeutic peptides to the development of diagnostic tools and research reagents. Its reliability in SPPS makes it a preferred component for researchers worldwide. When considering the purchase of this compound, understanding its role in mitigating side reactions and improving yields is crucial for laboratory planning and budget allocation. NINGBO INNO PHARMCHEM CO.,LTD. offers this vital intermediate at competitive prices, ensuring researchers have access to the materials they need for their groundbreaking work.

By providing detailed information about the synthesis, properties, and applications of Boc-Asn(Trt)-OH, NINGBO INNO PHARMCHEM CO.,LTD. aims to empower scientists. Whether you are involved in drug discovery, biochemical research, or materials science, this versatile amino acid derivative is an invaluable asset for achieving precise and efficient chemical synthesis.