The field of peptide research is constantly pushing boundaries, seeking to create novel molecules with specific biological activities. Central to this endeavor is the reliable and efficient synthesis of peptide chains. NINGBO INNO PHARMCHEM CO.,LTD. contributes significantly to this progress by supplying essential reagents such as Boc-Asn(Trt)-OH. This N-alpha-Boc-N-gamma-trityl-L-asparagine, identified by CAS 132388-68-2, is crucial for researchers aiming to advance peptide-based discoveries.

The incorporation of asparagine residues into peptide sequences presents unique challenges due to the reactivity of its side chain. The potential for aspartimide formation can compromise the purity and yield of the synthesized peptide, hindering research efforts. Boc-Asn(Trt)-OH addresses this challenge effectively. By employing a trityl (Trt) protecting group on the asparagine side chain, this derivative prevents the dreaded cyclization reaction. This robust protection, combined with the alpha-amino Boc protection, ensures that the asparagine residue integrates seamlessly into the peptide backbone during Solid-Phase Peptide Synthesis (SPPS).

Moreover, the enhanced solubility of Boc-Asn(Trt)-OH in common SPPS solvents is a significant benefit. This improved solubility facilitates more efficient coupling steps, leading to higher overall yields and a cleaner reaction profile. For researchers, this translates to less time spent on purification and a more reliable supply of target peptides for further study. The ability to purchase high-quality Boc-Asn(Trt)-OH at a reasonable price point is a key factor for academic and industrial labs alike.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing the peptide research community with top-tier chemical intermediates. Our Boc-Asn(Trt)-OH is manufactured to exacting standards, ensuring the purity and reliability necessary for cutting-edge peptide research. By supplying this vital reagent, we empower scientists to explore new frontiers in peptide chemistry, contributing to the development of innovative solutions in medicine, biology, and beyond.