NINGBO INNO PHARMCHEM CO.,LTD. is committed to illuminating the scientific landscape of natural compounds, and Dihydromyricetin (DHM), also known as Ampelopsin, from Vine Tea Extract, is a prime subject of our exploration. DHM’s biological activities span a wide range, from fundamental antioxidant functions to complex immune modulation.

At its core, Dihydromyricetin is a potent antioxidant. Scientific investigations have confirmed its efficacy in scavenging free radicals, thereby mitigating oxidative stress within the body. This fundamental property is crucial for cellular health and plays a role in preventing age-related damage and the onset of various chronic diseases. The antioxidant capabilities of DHM are a cornerstone of its use in health supplements, contributing to overall vitality and cellular protection.

Complementing its antioxidant action are DHM's notable anti-inflammatory properties. Chronic inflammation is implicated in a multitude of health issues, and DHM's ability to reduce inflammatory markers contributes to a more balanced physiological state. This combined antioxidant and anti-inflammatory profile makes DHM a valuable ingredient for formulations aimed at supporting general well-being and addressing conditions where inflammation is a key factor.

More recently, scientific research has delved into DHM's role as an immune modulator. Studies are uncovering how DHM influences key components of the immune system, such as natural killer (NK) cells. For instance, research in the context of liver health has shown that DHM can enhance the activation and function of hepatic NK cells. This modulation is believed to occur through complex signaling pathways, including the aryl hydrocarbon receptor (AhR), NF-κB, and STAT3, leading to increased production of immune signaling molecules like interferon-gamma (IFN-γ). This immune-enhancing effect is significant, potentially contributing to the body's defense mechanisms against disease and aiding in tissue repair, such as mitigating liver fibrosis.

The scientific journey of dihydromyricetin showcases its transition from a recognized antioxidant to a compound with complex immunomodulatory capabilities. Its multifaceted actions, including its role in autophagy induction, hangover relief, and its influence on immune cells, highlight its broad therapeutic potential. As research continues to unfold, DHM is poised to remain a key ingredient for companies focusing on science-backed natural health solutions.