2-Bromo-4-methoxyaniline: Synthesis, Properties, and Applications as a Key Organic Intermediate
Discover the indispensable role of 2-Bromo-4-methoxyaniline in advancing modern organic synthesis and pharmaceutical development.
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2-Bromo-4-methoxyaniline
2-Bromo-4-methoxyaniline (CAS: 32338-02-6) is a critical organic synthesis intermediate, prized for its unique combination of a bromine atom and a methoxy group on an aniline scaffold. This structure provides diverse reactivity, making it a cornerstone for creating complex molecules in the pharmaceutical and agrochemical industries. Its consistent high purity (≥98.0%) ensures reliable outcomes in sensitive synthetic processes.
- Introduction to 2-Bromo-4-methoxyaniline: This compound is instrumental in the organic synthesis of various fine chemicals. Its molecular formula C7H8BrNO and molecular weight of 202.048 contribute to its utility as a versatile building block.
- Chemical Properties and Specifications: Exhibiting a density of 1.5±0.1 g/cm³ and a boiling point of 265.1±20.0 °C, it is relatively stable. Its low vapor pressure and specific refractive index (1.596) are important for handling and analytical applications.
- Applications in Organic Synthesis: Primarily used as an intermediate, it facilitates the creation of complex molecules through various chemical transformations, particularly in creating pharmaceutical intermediates.
- Manufacturing and Supply Chain Excellence: Typically packaged in 25 kg drums, it can be customized, reflecting the flexibility of a leading supplier. Storage in cool, ventilated conditions preserves product integrity.
Key Advantages
Versatile Reactivity
The strategic placement of bromine and methoxy groups allows for a wide range of chemical transformations, making it a vital component for fine chemical synthesis.
High Purity and Consistency
Assay levels of ≥98.0% ensure reliable performance in demanding pharmaceutical intermediate synthesis, minimizing batch-to-batch variability.
Facilitates Complex Molecule Synthesis
Acts as a crucial building block for creating complex organic structures, essential for developing novel drugs and agrochemicals.
Key Applications
Pharmaceutical Research
Serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs), contributing to the development of new therapeutic agents.
Agrochemical Development
Used in the creation of compounds designed to protect crops and enhance agricultural productivity.
Specialty Chemical Production
A valuable building block for various specialty chemicals requiring precise molecular structures and reactivity.
Academic Research
Enables exploration of new synthetic pathways and the development of novel molecules in academic settings, leveraging its predictable reactivity.