2-Bromobenzamide: Synthesis, Properties, and Applications in Organic Chemistry

Explore the versatile uses of this crucial organic intermediate in advanced chemical synthesis.

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Advantages of Using 2-Bromobenzamide

Versatile Reactivity

The presence of both a bromine atom and an amide group on the benzene ring offers a wide array of chemical transformations, facilitating complex organic synthesis.

Key Building Block

As a key building block, it is instrumental in the 2-bromobenzamide synthesis of advanced materials and active pharmaceutical ingredients.

Facilitates Advanced Synthesis

Its utility in palladium-catalyzed synthesis of phenanthridinones highlights its importance in modern synthetic methodologies.

Key Applications

Substituted Isoindolin-1-ones

2-Bromobenzamide is utilized in microwave-assisted one-pot synthesis to create a variety of substituted 3-(phenylmethylene)isoindolin-1-ones, demonstrating its role in efficient synthesis strategies.

Phenanthridinones Synthesis

The compound plays a role in palladium-catalyzed reactions for the synthesis of phenanthridinones, a class of compounds with significant biological activities.

Iminophosphorane Ligands

Researchers employ 2-bromobenzamide in the development of novel water-soluble iminophosphorane ligands, advancing the field of coordination chemistry.

Pharmaceutical Intermediates

Its broad applicability makes CAS 4001-73-4 a valuable pharmaceutical intermediate, contributing to the development of new drug candidates.