Ethyl (S)-4-Chloro-3-Hydroxybutyrate: A Vital Pharmaceutical Intermediate
Discover the key role of this chiral compound in advanced pharmaceutical synthesis and drug development.
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Ethyl (S)-4-Chloro-3-Hydroxybutyrate
This compound is a cornerstone in the synthesis of critical medications, particularly recognized for its role in the creation of Atorvastatin and Atorvastatin calcium, vital for managing cholesterol levels. Its precise chiral structure is essential for ensuring the efficacy and safety of these life-saving drugs. As a light yellow liquid, it offers a high purity level, making it a reliable choice for complex pharmaceutical manufacturing processes and advanced chemical research.
- Introduction to Ethyl S-4-Chloro-3-Hydroxybutyrate: This chiral building block for pharmaceuticals, identified by CAS 86728-85-0, is indispensable for creating enantiomerically pure compounds.
- Role in Atorvastatin Production: As an intermediate for Atorvastatin calcium, it directly contributes to effective cholesterol-lowering treatments.
- Chemical and Physical Characteristics: Its molecular formula (C6H11ClO3) and liquid state ensure stability and versatility in various processing environments.
- Significance in Pharmaceutical Industry: Its high purity (typically >99%) and specific rotation make it a sought-after component for drug development, bridging raw chemistry with medicine.
Key Advantages
Precision in Synthesis
Leveraging its specific chiral structure, this intermediate allows for the highly precise synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), crucial for drug efficacy and safety.
Essential for Cholesterol Management Drugs
The compound is a critical building block in the production of statins like Atorvastatin, addressing a significant global health need for cardiovascular disease treatment.
Reliability and Purity
With a purity degree typically exceeding 99%, it provides manufacturers with the assurance of consistent quality, minimizing impurities and ensuring successful downstream synthesis processes.
Key Applications
Pharmaceutical Synthesis
Acts as a vital chiral building block for producing a range of Active Pharmaceutical Ingredients (APIs), including statins for cardiovascular health.
Chemical Research
Utilized in laboratories for developing novel chemical entities and exploring new synthetic pathways, contributing to advancements in medicinal chemistry.
Drug Development
Essential intermediate in the synthesis of drugs like Atorvastatin and Atorvastatin calcium, playing a key role in managing conditions such as hypercholesterolemia.
Biochemical Applications
Serves as a versatile precursor in biochemical research for understanding metabolic pathways and creating complex bioactive molecules.