Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate: A Key Pharmaceutical Intermediate
Discover the critical role of this advanced chemical in the synthesis of vital HMG-CoA reductase inhibitors like Rosuvastatin.
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![Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]](https://www.nbinno.com/2025/webimg/gemini_688bd9ce48f4b_1753995726.png)
Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate
This compound is a high-purity fine chemical, serving as a vital intermediate in the complex synthesis pathways of pharmaceutical active ingredients. Its precise molecular structure makes it indispensable for the production of effective therapeutic agents.
- Exploring the methyl 5-Oxorosuvastatin intermediate is crucial for understanding the intricacies of Rosuvastatin synthesis.
- Leveraging CAS 147118-39-6 as a pharmaceutical material ensures the development of effective cardiovascular drugs.
- The chemical synthesis of Rosuvastatin relies heavily on the availability and quality of this specific intermediate.
- This fine chemical intermediate for cardiovascular drugs is manufactured to stringent purity standards.
Key Advantages
Enhanced Synthesis Efficiency
The use of this specific pharmaceutical intermediate significantly streamlines the Rosuvastatin manufacturing process, leading to higher yields and reduced production times. This is essential for meeting market demands for cholesterol-lowering medications.
Guaranteed Purity and Quality
As a fine chemical, it is produced with exceptional purity, a critical factor in pharmaceutical synthesis. High purity ensures the final drug product is safe and effective, adhering to strict regulatory requirements and contributing to successful drug development.
Enabling Therapeutic Innovation
This intermediate is fundamental for creating HMG-CoA reductase inhibitors, a class of drugs essential for managing cardiovascular health. Its availability supports ongoing research and development in creating new and improved treatments for patients.
Key Applications
Rosuvastatin Production
This chemical is a cornerstone in the multi-step process to manufacture Rosuvastatin, a widely prescribed medication for hypercholesterolemia. Its role in the synthesis pathway is critical for the efficacy of the final product.
Cardiovascular Drug Development
It serves as a building block for various cardiovascular drugs that target cholesterol metabolism. This contributes to the broader field of medicinal chemistry focused on improving heart health and preventing related diseases.
Advanced Organic Synthesis
Beyond its primary pharmaceutical application, this compound can be utilized in advanced organic synthesis projects requiring complex pyrimidine derivatives and specific stereochemistry, driving innovation in chemical research.
Research and Development
Its availability supports R&D efforts in discovering new therapeutic applications or developing more efficient synthesis routes for statin-class drugs, contributing to the advancement of pharmaceutical science.