O-Phosphoethanolamine: A Deep Dive into its Chemistry, Applications, and Biological Significance
Explore the multifaceted nature of O-Phosphoethanolamine, a vital compound impacting cellular functions and human health.
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O-Phosphoethanolamine
O-Phosphoethanolamine (PEA), a crucial intermediate in phospholipid biosynthesis, holds significant importance in various biological processes. Its molecular formula, C2H8NO4P, and molecular weight of 141.06300 underscore its fundamental role in cellular biochemistry. This white powder, with a melting point of 241-243 °C, serves as a foundational element for glycerophospholipids and sphingolipids, vital for maintaining cell membrane integrity and fluidity. Its involvement extends to cellular signaling pathways and neurological functions, making it a compound of great interest in scientific research and pharmaceutical development.
- Discover the key role of O-Phosphoethanolamine in phospholipids metabolism, influencing cellular health.
- Understand O-Phosphoethanolamine's implications in myelination and its relation to neurological conditions like Alzheimer's disease.
- Explore how O-Phosphoethanolamine contributes to cartilage structure and function, vital for skeletal health.
- Learn about the biological significance of PEA as an indicator of neural membrane synthesis and signal transduction processes.
Key Advantages
Comprehensive Biological Role
O-Phosphoethanolamine's involvement in the biosynthesis of essential phospholipids highlights its fundamental contribution to cellular structure and function, impacting everything from membrane fluidity to signal transduction.
Neuroscience and Health Link
Research indicates that O-Phosphoethanolamine levels are correlated with brain phospholipid turnover and can serve as a potential biomarker in neurological conditions, underscoring its importance in brain health.
Skeletal Health Contribution
The compound's role in cartilage structure and function, particularly in bone and teeth, makes O-Phosphoethanolamine a significant factor in maintaining skeletal integrity and health.
Key Applications
Pharmaceutical Research
As a vital intermediate in phospholipid biosynthesis, O-Phosphoethanolamine is a key compound for researchers developing new pharmaceutical interventions targeting metabolic and neurological disorders.
Biochemical Analysis
Understanding the metabolism of O-Phosphoethanolamine and its associated enzymes provides critical insights into cellular processes, making it valuable for biochemical and metabolic pathway studies.
Neurological Studies
Its role in myelination and potential links to diseases like Alzheimer's and Huntington's make O-Phosphoethanolamine a compound of significant interest in neurological research and the development of treatments.
Biomarker Discovery
Elevated levels of O-Phosphoethanolamine in urine can be indicative of certain conditions, positioning it as a potential biomarker for early diagnosis and monitoring of diseases such as hypophosphatasia.
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