Advancing Breast Cancer Care with Alpelisib
Discover the targeted therapy revolutionizing treatment for advanced breast cancer.
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Alpelisib
Alpelisib is a crucial targeted therapy drug, categorized as a PI3K inhibitor, designed to combat advanced or metastatic, hormone receptor-positive breast cancer. It plays a vital role by specifically targeting and blocking the PI3K pathway within cancer cells, a pathway often overactive due to PIK3CA gene mutations, which can lead to resistance to hormonal therapies.
- Explore the efficacy of Alpelisib for breast cancer patients, focusing on managing hormone receptor-positive subtypes.
- Understand how this PI3K inhibitor works in conjunction with fulvestrant to inhibit cancer cell growth pathways.
- Learn about the crucial role of the PIK3CA gene mutation in determining treatment suitability for advanced breast cancer.
- Discover the importance of comprehensive side effect management strategies for targeted therapy for metastatic breast cancer.
Key Advantages
Targeted Action
Alpelisib offers a precise approach to treating breast cancer by inhibiting the PI3K pathway, a critical factor in the progression of hormone receptor-positive, HER2-negative metastatic disease.
Improved Patient Outcomes
When combined with fulvestrant, Alpelisib demonstrates significant potential in keeping cancer from growing, offering a valuable advancement in metastatic breast cancer treatment options.
Oral Administration
As an oral pill, Alpelisib provides a more convenient treatment regimen for patients, allowing for home-based administration alongside the necessary hormonal therapy.
Key Applications
Advanced Breast Cancer Therapy
Specifically indicated for patients with advanced or metastatic, hormone receptor-positive breast cancer that has progressed during or after hormonal therapy, especially those with a PIK3CA gene mutation.
Oncology Research & Development
Serves as a key active pharmaceutical ingredient (API) in ongoing oncology research, aiding the development of new treatment protocols and understanding of cancer resistance mechanisms.
Pharmaceutical Manufacturing
Produced as a high-quality pharmaceutical chemical, meeting stringent standards for use in the synthesis of life-saving medications within the pharmaceutical industry.
Personalized Medicine
Facilitates personalized medicine approaches by targeting specific genetic mutations like PIK3CA, tailoring treatment to individual patient profiles for maximum efficacy.