NSI-189 Phosphate: A Neurogenic Compound for Depression and Cognitive Enhancement
Exploring the therapeutic potential of a novel neurogenic compound for treating depression and improving cognitive function.
Get a Quote & SampleProduct Core Value
NSI-189 Phosphate
NSI-189 Phosphate is a pioneering neurogenic compound designed to stimulate neurogenesis and neuroplasticity within the hippocampus. Developed to address the limitations of existing treatments for Major Depressive Disorder (MDD), it offers a novel mechanism of action independent of monoamine pathways. While its effects on clinician-rated scales like MADRS have shown mixed results, NSI-189 consistently demonstrates significant improvements in patient-reported depressive symptoms and cognitive functions, making it a promising avenue for comprehensive mental health treatment.
- Investigating the efficacy of NSI-189 phosphate in clinical trials provides insights into novel treatment for depression.
- As a neurogenic compound for depression, NSI-189 works by stimulating the generation of new neurons in the hippocampus.
- The mechanism of action of NSI-189 phosphate targets hippocampal neurogenesis and neuroplasticity for therapeutic benefit.
- Exploring Alto Neuroscience's work with NSI-189 highlights advancements in cognitive enhancement for patients with depression.
Key Advantages
Novel Mechanism
Unlike traditional antidepressants, NSI-189 phosphate operates via a neurogenic pathway, potentially offering a new approach to treating depression and related cognitive impairments.
Cognitive Improvement
Research suggests that NSI-189 phosphate can lead to significant enhancements in cognitive functions, such as memory and executive function, which are often compromised in patients with MDD.
Favorable Tolerability
Clinical trials indicate that NSI-189 phosphate is generally well-tolerated across various doses, with a good safety profile and minimal serious adverse effects.
Key Applications
Depression Treatment
NSI-189 Phosphate is being studied as a primary treatment for Major Depressive Disorder, aiming to alleviate mood symptoms through its neurogenic properties.
Cognitive Enhancement
The compound shows promise in improving cognitive functions such as memory and executive functioning, addressing a common challenge in depression management.
Neurogenesis Stimulation
By directly stimulating the generation of new neurons in the hippocampus, NSI-189 Phosphate aims to reverse the neural atrophy associated with depression.
Research in CNS Disorders
Beyond depression, NSI-189 Phosphate is explored for its potential in other central nervous system disorders, highlighting its versatile neurotrophic effects.