Sacubitril Hemicalcium Salt: Potent Neprilysin Inhibitor for Cardiovascular Health
Discover the advanced pharmaceutical properties of Sacubitril Hemicalcium Salt, a key ingredient in modern heart failure treatments.
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Sacubitril Hemicalcium Salt
Sacubitril Hemicalcium Salt, also known as AHU-377, is a high-purity active pharmaceutical ingredient (API) crucial for cardiovascular treatments. It functions as a prodrug that is metabolized into an active neprilysin inhibitor, playing a pivotal role in managing heart failure. Its efficacy in reducing cardiovascular death risk and hospitalization makes it a cornerstone in advanced cardiac care.
- Explore the API chemical properties of Sacubitril Hemicalcium Salt, understanding its stability and interactions.
- Learn how AHU-377 acts as a neprilysin inhibitor, impacting natriuretic peptide levels for better cardiovascular health.
- Investigate its use as a heart failure treatment drug, contributing to improved patient outcomes and quality of life.
- Discover the advantages of using Sacubitril Hemicalcium Salt for its potent prodrug conversion into an active neprilysin inhibitor.
Key Advantages
Enhanced Cardiovascular Efficacy
Leveraging the properties of Sacubitril hemicalcium salt, patients experience significant improvements in managing heart failure, as demonstrated in clinical studies.
Potent Neprilysin Inhibition
As a prodrug, it effectively inhibits neprilysin, contributing to the elevation of beneficial natriuretic peptides, a critical mechanism in cardiovascular therapy.
High Purity and Quality Standards
Our Sacubitril hemicalcium salt meets stringent purity requirements (≥ 98.0% HPLC), ensuring reliability and effectiveness as an API for pharmaceutical formulations.
Key Applications
Heart Failure Management
Sacubitril hemicalcium salt is a vital component in combination therapies for heart failure with reduced ejection fraction, improving patient prognosis.
Cardiovascular Therapy Advancement
It represents a significant advancement in cardiovascular drug development, offering a novel mechanism for managing complex cardiac conditions.
API in Pharmaceutical Manufacturing
As a high-quality API, it is essential for the formulation of life-saving medications, underscoring the importance of reliable API chemical properties.
Antihypertensive Applications
Beyond heart failure, its mechanism of action suggests potential benefits in managing hypertension and related cardiovascular risks.