Afamelanotide, identified by its CAS number 75921-69-6 and often referred to as Melanotan I (MT-1), is a synthetic peptide that holds significant promise in the fields of dermatology and photomedicine. As an analogue of alpha-melanocyte-stimulating hormone (α-MSH), it plays a crucial role in regulating skin pigmentation and offers protective benefits against UV radiation.

The primary mechanism through which Afamelanotide exerts its effects is by stimulating the melanocortin 1 receptor (MC1R). This activation triggers melanogenesis, the process of melanin production within melanocytes. Melanin is the pigment responsible for skin color and serves as a natural defense against the damaging effects of UV light. For individuals with Erythropoietic Protoporphyria (EPP), a condition marked by extreme photosensitivity, Afamelanotide has demonstrated an ability to increase pain-free light exposure, significantly improving their quality of life. Understanding afamelanotide for erythropoietic protoporphyria is central to appreciating its therapeutic potential.

Typically supplied as a high-purity lyophilized powder, Afamelanotide is ideally suited for laboratory research and the development of novel treatments. The question of what is afamelanotide mt-1 is answered by its identity as a potent melanocortin receptor agonist. Scientific investigations are continually exploring how does afamelanotide work in greater detail, including its effects on cellular signaling and DNA repair pathways.

The research applications of synthetic peptide afamelanotide extend beyond EPP. Its photoprotective properties are being investigated for a range of dermatological conditions and for general skin health enhancement. The availability of afamelanotide mt-1 lyophilized powder facilitates crucial research into these potential applications.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting scientific advancement by providing researchers with high-quality compounds like Afamelanotide. Its detailed characterization and consistent quality make it a reliable subject for studies exploring the intricacies of melanogenesis, photoprotection, and the development of next-generation peptide therapeutics.