Cidofovir, identified by CAS NO: 113852-37-2, is a synthetic antiviral compound that has demonstrated significant efficacy in combating severe viral infections. Its primary therapeutic role is in the management of Cytomegalovirus (CMV) infections, particularly CMV retinitis, a condition that can lead to vision impairment in immunocompromised patients, often those diagnosed with HIV/AIDS. The drug's antiviral prowess stems from its unique structure as a nucleoside analogue. Upon entering target cells, Cidofovir is converted into its active form, cidofovir diphosphate, by cellular enzymes. This active metabolite acts as a potent inhibitor of viral DNA polymerase, an enzyme essential for viral replication. By competitively inhibiting this enzyme and being incorporated into the viral DNA, Cidofovir effectively halts the production of new viral particles.

The clinical significance of Cidofovir is amplified by its ability to treat infections that may be resistant to other antiviral agents, making it a vital option for salvage therapy. Beyond its established use against CMV, ongoing research and clinical observations are highlighting its potential in dermatological applications. Topical formulations of Cidofovir are being explored for their efficacy in treating various viral skin diseases, including warts (such as anogenital warts) and molluscum contagiosum. These investigations suggest a broader spectrum of antiviral activity for the compound. For professionals and researchers seeking to utilize Cidofovir, understanding its availability and sourcing from reliable manufacturers and suppliers is crucial. When looking to buy Cidofovir, identifying reputable chemical suppliers, particularly from manufacturing hubs like China, ensures access to a high-quality product. The price of Cidofovir can vary, making diligent supplier research essential for both cost-effectiveness and product integrity.