The Legacy of Tacrine: A Deep Dive for Pharmaceutical Researchers
Tacrine, identified by its CAS number 321-64-2, holds a significant place in the history of Alzheimer's disease treatment. As a pioneering cholinesterase inhibitor, it was one of the first drugs approved to help manage cognitive decline associated with this debilitating condition. This article delves into the chemical nature of Tacrine, its pharmacological actions, and its impact on subsequent drug development.
Tacrine functions by inhibiting the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine in the brain. Acetylcholine is a neurotransmitter vital for learning and memory. By boosting its levels, Tacrine aimed to improve cognitive functions in patients. However, its clinical utility was eventually limited by significant side effects, most notably hepatotoxicity, leading to its withdrawal from many markets and the development of newer, better-tolerated alternatives.
For researchers in the pharmaceutical sector, understanding Tacrine's properties and its journey from development to market is invaluable. It provides critical insights into the challenges and advancements in treating neurodegenerative diseases. If you are looking to buy Tacrine CAS 321-64-2 for historical research or comparative studies, it's important to source it from reputable suppliers. We, as a leading tacrine manufacturer in China, are committed to providing high-quality chemical intermediates for your research needs. Exploring the tacrine price FOB China can also be beneficial for budget planning in research projects.
The compound's chemical formula is C13H14N2, and it typically appears as a white to light yellow crystalline powder. Its ability to cross the blood-brain barrier was a key feature enabling its central nervous system effects. While not a first-line treatment today, the study of acetylcholinesterase inhibitor Tacrine continues to inform the design of new therapeutic strategies for cognitive disorders. For those interested in its availability and specifications, investigating the tacrine price FOB China from trusted tacrine manufacturers in China is a recommended first step for procurement.
Tacrine functions by inhibiting the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine in the brain. Acetylcholine is a neurotransmitter vital for learning and memory. By boosting its levels, Tacrine aimed to improve cognitive functions in patients. However, its clinical utility was eventually limited by significant side effects, most notably hepatotoxicity, leading to its withdrawal from many markets and the development of newer, better-tolerated alternatives.
For researchers in the pharmaceutical sector, understanding Tacrine's properties and its journey from development to market is invaluable. It provides critical insights into the challenges and advancements in treating neurodegenerative diseases. If you are looking to buy Tacrine CAS 321-64-2 for historical research or comparative studies, it's important to source it from reputable suppliers. We, as a leading tacrine manufacturer in China, are committed to providing high-quality chemical intermediates for your research needs. Exploring the tacrine price FOB China can also be beneficial for budget planning in research projects.
The compound's chemical formula is C13H14N2, and it typically appears as a white to light yellow crystalline powder. Its ability to cross the blood-brain barrier was a key feature enabling its central nervous system effects. While not a first-line treatment today, the study of acetylcholinesterase inhibitor Tacrine continues to inform the design of new therapeutic strategies for cognitive disorders. For those interested in its availability and specifications, investigating the tacrine price FOB China from trusted tacrine manufacturers in China is a recommended first step for procurement.
Perspectives & Insights
Logic Thinker AI
“This article delves into the chemical nature of Tacrine, its pharmacological actions, and its impact on subsequent drug development.”
Molecule Spark 2025
“Tacrine functions by inhibiting the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine in the brain.”
Alpha Pioneer 01
“However, its clinical utility was eventually limited by significant side effects, most notably hepatotoxicity, leading to its withdrawal from many markets and the development of newer, better-tolerated alternatives.”