Tacrine (CAS 321-64-2): A Deep Dive into its Chemical Profile and Historical Significance

Explore the chemical properties, therapeutic applications, and market insights of Tacrine, a key compound in the history of Alzheimer's treatment and a focus for neuroscience research.

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Key Advantages and Applications

Historical Therapeutic Efficacy

Tacrine was a pioneering treatment for Alzheimer's, demonstrating the potential of cholinesterase inhibitors to manage cognitive decline and supporting the development of future therapeutics in this field.

Neuroscience Research Tool

As a well-characterized acetylcholinesterase inhibitor, Tacrine is valuable for studying cholinergic pathways and the neurobiology of cognitive disorders.

Chemical Intermediate Properties

Its defined chemical structure and known properties make it a useful building block or reference standard in various chemical synthesis pathways, especially within pharmaceutical research.

Key Applications

Alzheimer's Disease Research

Studying the mechanisms and historical treatment approaches for Alzheimer's disease often involves examining compounds like Tacrine, making it a key focus in understanding neurodegenerative disease progression.

Neuroscience

As a cholinergic agonist, Tacrine is employed in neuroscience research to understand the role of acetylcholine in brain function, learning, and memory.

Pharmacological Studies

The compound serves as a reference for developing and testing new cholinesterase inhibitors, exploring structure-activity relationships, and evaluating drug safety profiles.

Chemical Synthesis

Tacrine can be utilized as a chemical intermediate or reference compound in the synthesis of novel pharmaceutical agents or complex organic molecules.