The potential of natural compounds like Lumbrokinase is being further unlocked through advancements in biotechnology. Researchers are exploring methods to enhance the production and purity of this fibrinolytic enzyme using recombinant DNA technology in host organisms like E. coli. Strategies such as protein fusion, using tags like SUMO, have shown promise in increasing the yield and solubility of active Lumbrokinase, making it more accessible for therapeutic use. This scientific endeavor aims to harness the power of nature's solutions through innovative bioengineering, potentially leading to more effective and cost-efficient treatments for various health conditions. The development of recombinant Lumbrokinase highlights the synergy between natural products and modern biotechnology.