As a leading B2B chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing innovative ingredients for the cosmetic industry. Today, we delve into the science behind TXC, or Cetyl Tranexamate HCl (CAS 913541-96-5), a cutting-edge active ingredient revolutionizing the skin brightening and anti-pigmentation market.

Understanding TXC: The Next Generation of Tranexamic Acid Derivatives

Cetyl Tranexamate HCl is an esterification derivative of tranexamic acid, meticulously engineered to overcome the limitations of its precursor. The introduction of lipid hydrocarbon chains into its molecular structure significantly enhances its oil solubility and, crucially, its transdermal absorption capacity. This structural innovation allows TXC to penetrate the skin layers much more effectively, delivering its active benefits deeper and more persistently than traditional tranexamic acid.

Mechanism of Action: How TXC Delivers Superior Results

TXC operates through multiple sophisticated pathways to achieve its remarkable skin-brightening effects:

  • Melanin Inhibition: TXC acts by competitively inhibiting tyrosinase activity, a key enzyme responsible for melanin production. By blocking the oxidation of melanin precursors, it effectively reduces the synthesis of pigment in the skin. This direct action on melanin production is a cornerstone of its efficacy for skin lightening.
  • Indirect Pigmentation Control: Beyond direct inhibition, TXC also plays a role in reducing inflammation. It works by inhibiting the conversion of plasminogen to plasmin and decreasing the release of inflammatory mediators like prostaglandin E2. This indirect pathway helps to prevent and reduce pigmentation triggered by inflammation and UV exposure, a common concern for many consumers.
  • Anti-angiogenesis and PIH Prevention: The ingredient's ability to inhibit the expression of vascular endothelial growth factor (VEGF) is crucial in preventing post-inflammatory hyperpigmentation (PIH). This makes it an invaluable component for formulations aimed at calming the skin and preventing discoloration after irritation or injury.

Unparalleled Penetration and Efficacy for Cosmetic Formulations

Experimental data highlight TXC's superior performance, demonstrating a permeability that is 97 times greater than traditional tranexamic acid. Once absorbed into the skin, TXC is gradually activated by esterase enzymes naturally present in skin cells, converting into its active form. This sustained release mechanism ensures a continuous effect that can last up to 12 hours, offering a significant advantage for product developers seeking long-lasting benefits for their customers. Its effectiveness has been quantified, with some studies suggesting it can be up to 60 times more effective than plain tranexamic acid for skin lightening.

Applications and Sourcing from a Trusted Manufacturer

The unique properties of Cetyl Tranexamate HCl make it an ideal ingredient for a range of high-end cosmetic products. It is frequently incorporated into:

  • High-End Essences: To boost the brightening and anti-spot efficacy of premium serums.
  • Advanced Face Creams: For anti-aging and whitening formulas that require potent pigment control.
  • Skin Lightening Lotions: To create effective products that fade dark spots, melasma, and uneven skin tone.

Recommended usage levels typically range from 1% to 3%. When considering purchasing this ingredient, partnering with a reliable manufacturer and supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures you receive high-purity TXC, backed by stringent quality control. We understand the critical role of ingredient sourcing in developing successful cosmetic products. If you are looking to buy high-quality TXC or other advanced cosmetic raw materials, we are your trusted partner in China, offering competitive pricing and consistent supply.

For procurement inquiries or to request a sample, please contact us today. Discover how our Cetyl Tranexamate HCl can elevate your next cosmetic innovation.