The pharmaceutical industry relies heavily on a robust supply of high-purity chemical intermediates to drive innovation and produce life-saving medications. Among these crucial building blocks is Ethanol, 2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxy)]bis-, 1,1'-diacetate, known by its CAS number 19224-29-4. This article highlights its importance for research scientists and pharmaceutical manufacturers seeking reliable sourcing options.

The Significance of CAS 19224-29-4 in API Development

Ethanol, 2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxy)]bis-, 1,1'-diacetate is a sophisticated organic molecule that acts as a key intermediate in the complex synthesis pathways of various Active Pharmaceutical Ingredients (APIs). Its intricate structure, featuring aromatic rings and ester functionalities, allows for targeted chemical modifications, enabling medicinal chemists to construct complex drug molecules efficiently.

Key contributions to pharmaceutical synthesis include:

  • Scaffolding for Complex Molecules: The compound provides a pre-formed structural framework that reduces the number of synthetic steps required to reach target APIs. This efficiency is critical for cost-effective drug development and manufacturing.
  • Enabling Novel Drug Delivery Systems: Beyond API synthesis, this intermediate is being explored for its potential in developing advanced drug delivery systems. Its chemical properties can be leveraged to create matrices that offer controlled release of therapeutic agents, improving efficacy and reducing side effects. Researchers often look for this to improve bioavailability of poorly soluble drugs.
  • High Purity for Critical Applications: The requirement for high purity (≥99%) in pharmaceutical manufacturing cannot be overstated. Impurities can compromise the safety and efficacy of the final drug product. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensure that this intermediate meets stringent quality standards.

Procurement Best Practices for Pharmaceutical Companies

When sourcing pharmaceutical intermediates like CAS 19224-29-4, several factors are essential for R&D scientists and procurement managers:

  • Supplier Qualification: It is crucial to partner with manufacturers who adhere to Good Manufacturing Practices (GMP) principles, even for intermediates. Thoroughly vet suppliers for their quality control systems, production capacity, and regulatory compliance.
  • Traceability and Documentation: Ensure that comprehensive documentation, including Certificates of Analysis (CoA) and material safety data sheets (MSDS), is readily available. This traceability is vital for regulatory submissions and quality assurance.
  • Consistency in Supply: The drug development pipeline requires unwavering consistency. Securing a reliable supplier that can guarantee consistent quality and timely delivery of CAS 19224-29-4 is paramount.
  • Cost-Effectiveness: While quality is non-negotiable, cost remains a significant factor. Identifying suppliers, particularly from China, that can offer competitive pricing without compromising on purity is key to managing R&D and manufacturing budgets.

For pharmaceutical companies looking to buy Ethanol, 2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxy)]bis-, 1,1'-diacetate (CAS 19224-29-4), NINGBO INNO PHARMCHEM CO.,LTD. offers a dependable source. We are committed to supplying high-quality intermediates that support the advancement of pharmaceutical research and manufacturing. Contact us to discuss your requirements and secure a consistent supply of this vital chemical.