For professionals in the chemical industry, sourcing reliable intermediates is paramount to successful product development and manufacturing. One such crucial compound is 2-Methyl-5-nitrophenol (CAS 5428-54-6). This article aims to provide a detailed understanding of this versatile chemical, its properties, synthesis, and applications, highlighting its importance for procurement managers, R&D scientists, and formulators.

What is 2-Methyl-5-nitrophenol?
2-Methyl-5-nitrophenol, also known by synonyms such as 5-Nitro-o-cresol or 2-Hydroxy-4-nitrotoluene, is an organic compound characterized by its light yellow to brown powder appearance. With the molecular formula C7H7NO3 and a molecular weight of 153.14 g/mol, it serves as a fundamental building block in various chemical synthesis pathways. Its unique structure, featuring a methyl group at the ortho position and a nitro group at the meta position relative to the hydroxyl group, imparts specific reactivity highly sought after in industrial applications.

Key Applications in the Chemical Industry
The primary utility of 2-Methyl-5-nitrophenol lies in its role as a reactant for the preparation of pyranocarbazole alkaloids, which are significant in pharmaceutical research. Beyond pharmaceuticals, it is a vital intermediate in the manufacturing of dyes, pigments, and particularly hair dyes. Its contribution to the colorant industry underscores its commercial importance.

Sourcing and Manufacturing Considerations
When you are looking to buy 2-Methyl-5-nitrophenol, understanding its specifications and sourcing options is key. Manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., are leading suppliers of high-purity 2-Methyl-5-nitrophenol (typically 98% or higher). Sourcing from a reputable 2-Methyl-5-nitrophenol manufacturer ensures consistency in quality, reliable supply, and competitive 2-Methyl-5-nitrophenol price. As a trusted 2-Methyl-5-nitrophenol supplier, we cater to global demands with efficient logistics and quality assurance.

Synthesis and Properties
The synthesis of 2-Methyl-5-nitrophenol often involves the nitration of o-cresol using a mixture of nitric and sulfuric acids. Careful control of reaction conditions, including temperature and acid concentration, is crucial for optimizing yield and purity. Its physical properties, such as a melting point of 111-115°C, and slight solubility in chloroform and methanol, are important considerations for handling and formulation.

For businesses requiring a dependable supply of this critical intermediate, partnering with experienced manufacturers is essential. We invite you to inquire about our product specifications, availability, and to request a quote for your chemical sourcing needs.