For professionals in the flavor, fragrance, and chemical industries, a deep understanding of key compounds is essential. Ethyl Phenylacetate, identified by its Chemical Abstracts Service (CAS) number 101-97-3, is one such compound, renowned for its distinctive sweet, floral, and honey-like aroma. Delving into its chemical profile reveals why it is so widely utilized.

Chemically, Ethyl Phenylacetate is an ester formed from phenylacetic acid and ethanol. Its molecular formula is C10H12O2, and it has a molecular weight of 164.2 g/mol. It typically appears as a clear, colorless to pale yellowish liquid. Key physical properties include a boiling point of approximately 226-229 °C and a melting point of -29 °C, indicating it remains liquid under standard room temperature conditions. Its density is around 1.03 g/mL, and its refractive index is consistently reported around 1.497-1.499.

From a safety perspective, Ethyl Phenylacetate is generally considered moderately toxic by ingestion, with reported LD50 values in rats indicating a degree of caution is necessary. However, it is also categorized as a combustible liquid with a flash point of around 77 °C. Importantly, data suggests it is non-mutagenic and can be considered a 'greener' solvent, signifying a lower environmental and health hazard compared to many other organic solvents.

The regulatory status of Ethyl Phenylacetate is well-established, particularly within the food and flavor industries. It is listed by FEMA (Flavor and Extract Manufacturers Association) as GRAS (Generally Recognized As Safe) for use as a flavoring substance (FEMA Number 2452). It is also recognized by organizations like JECFA (Joint FAO/WHO Expert Committee on Food Additives), with a JECFA Number of 1009, and is permitted for use in food according to FDA regulations (21 CFR 172.515).

The sensory profile is a critical aspect of its chemical characterization. At low concentrations, it imparts sweet, floral, honey, rose, and cocoa notes, making it invaluable for flavorists and perfumers. Its odor detection threshold is relatively low, meaning even small amounts can significantly impact the sensory profile of a product. Understanding these chemical and sensory properties is crucial for effective sourcing and application of Ethyl Phenylacetate by manufacturers.