N-Isopropylacrylamide (NIPAM), identified by CAS number 2210-25-5, is a versatile monomer widely recognized for its role in creating advanced polymer materials, particularly those exhibiting temperature-sensitive behavior. Understanding its fundamental properties is crucial for chemists, researchers, and procurement specialists who are looking to purchase and utilize this compound effectively. As a dedicated manufacturer and supplier based in China, we aim to provide clear insights into NIPAM's characteristics and why sourcing from a trusted provider is advantageous.

Physically, N-Isopropylacrylamide is typically supplied as a white to light yellow crystalline powder or crystals. Its molecular formula is C6H11NO, and it has a molecular weight of approximately 113.16 g/mol. The melting point commonly falls within the range of 60-63°C, indicating it is a solid at room temperature under standard conditions. Its boiling point is around 89-92°C at 2 mm Hg, suggesting it has moderate volatility under reduced pressure.

Chemically, N-Isopropylacrylamide is an N-substituted acrylamide. The presence of the isopropyl group attached to the amide nitrogen is key to its most celebrated property: the temperature-dependent solubility of its polymer, poly(N-isopropylacrylamide) (pNIPAM). Polymers formed from NIPAM exhibit a Lower Critical Solution Temperature (LCST), usually around 33°C. Below this temperature, pNIPAM is readily soluble in water due to the favorable interactions between the polymer chains and water molecules, facilitated by the amide group. Above the LCST, hydrophobic interactions become dominant, leading to polymer chain aggregation and precipitation, or a significant shrinking of hydrogels.

This thermosensitivity makes N-Isopropylacrylamide an ideal monomer for applications requiring responsiveness to thermal stimuli. These include creating smart hydrogels for controlled drug delivery, designing temperature-responsive coatings, developing materials for tissue engineering, and formulating specialized membranes. For instance, when you search for monomers to build drug delivery systems that release medication at specific body temperatures, NIPAM is a prime candidate. Purchasing N-Isopropylacrylamide from a reputable manufacturer like ourselves ensures you receive material with the precise characteristics needed for these sensitive applications.

Solubility is another important property to consider. N-Isopropylacrylamide is slightly soluble in water but generally shows good solubility in many organic solvents such as methanol, ethanol, and acetone. This solubility profile is important for both polymerization processes and for handling the monomer during research or formulation. When considering where to buy NIPAM, it’s beneficial to partner with a supplier that can provide technical data sheets detailing solubility in various media.

As a leading supplier and manufacturer of N-Isopropylacrylamide in China, we are committed to delivering high-purity products that meet global standards. Our rigorous quality control processes ensure lot-to-lot consistency, which is critical for reproducible research and scalable production. We understand the importance of reliable chemical sourcing. If your work involves developing advanced polymers and responsive materials, consider us your trusted partner for purchasing N-Isopropylacrylamide (CAS 2210-25-5). Contact us today to discuss your chemical needs and obtain a quote.