The intersection of chemistry and biology, known as chemical biology, relies heavily on precisely engineered molecules to probe and manipulate biological systems. 7-Octyn-1-ol, with its CAS number 871-91-0, stands out as a particularly valuable reagent in this field due to its terminal alkyne group, which is ideally suited for bioorthogonal 'click' chemistry. As a manufacturer and supplier of essential research chemicals, we highlight the significant contributions of 7-Octyn-1-ol to advancing chemical biology research.

7-Octyn-1-ol in Chemical Biology Applications

The power of 7-Octyn-1-ol in chemical biology stems from its ability to be incorporated into biomolecules or used as a precursor for probes that can then be detected or manipulated using highly selective chemical reactions. The terminal alkyne is the key feature, enabling:

  • Molecular Probes for Pathway Analysis: Researchers can synthesize molecules containing the 7-octyn-1-ol scaffold, which are then used as activity-based probes (ABPs). These probes often feature a reactive group that binds to a specific enzyme or protein, and the terminal alkyne serves as a handle for attaching a reporter molecule (e.g., a fluorophore or biotin) via click chemistry. This allows for the visualization, enrichment, and identification of target biomolecules within complex biological contexts.
  • Site-Specific Labeling: The ability to label biomolecules at precise locations is critical for understanding their function. 7-Octyn-1-ol derivatives can be used to introduce alkyne handles onto proteins or nucleic acids. This can be achieved through genetic incorporation of unnatural amino acids bearing alkyne groups, or through chemical modification of specific sites on the biomolecule. Once labeled, these alkyne groups can react selectively with azide-functionalized reporter molecules, allowing for sensitive detection and analysis.
  • Drug Discovery and Development: In drug discovery, click chemistry, utilizing reagents like 7-Octyn-1-ol, is employed to rapidly synthesize and screen large libraries of potential drug candidates. The resulting triazole linkages are metabolically stable and can contribute to the binding affinity of a drug molecule.
  • Bioconjugation: The term 'bioconjugation' refers to the process of covalently linking molecules to biomolecules. 7-Octyn-1-ol, via its alkyne group and click chemistry, is a prime tool for creating these conjugates, which have applications in targeted drug delivery, diagnostics, and antibody-drug conjugates (ADCs).

Reliable Supply from a Trusted Partner

For researchers in chemical biology, the quality and availability of reagents like 7-Octyn-1-ol (CAS: 871-91-0) are paramount. Our company specializes in manufacturing and supplying high-purity chemicals that meet the stringent demands of research laboratories. We understand the importance of consistent product quality, competitive pricing, and a dependable supply chain. When you need to buy 7-Octyn-1-ol for your cutting-edge chemical biology research, we are your trusted source, ensuring you have the materials to drive your discoveries forward.