Organic chemistry is the science of carbon compounds, and at its core are versatile molecules that act as building blocks for complex structures. 7-Octyn-1-ol, with its distinctive terminal alkyne and primary alcohol functionalities (CAS: 871-91-0), is such a molecule, offering a broad spectrum of synthetic possibilities. As a manufacturer and supplier dedicated to providing high-quality fine chemicals, we highlight the significance of 7-Octyn-1-ol in modern organic synthesis.

Understanding 7-Octyn-1-ol: Structure and Properties

7-Octyn-1-ol is an eight-carbon chain molecule featuring a triple bond at the terminal position (C7-C8) and a hydroxyl group at the other end (C1). This bifunctionality is key to its utility. The terminal alkyne is amenable to a wide array of reactions, including click chemistry, Sonogashira couplings, and various addition reactions. The primary alcohol can undergo esterification, etherification, oxidation, or serve as a starting point for further chain elongation or functionalization.

Synthetic Routes and Production

The synthesis of 7-Octyn-1-ol often involves the isomerization of internal alkynes, such as 2-octyn-1-ol, to the terminal alkyne via an 'alkyne zipper' reaction. Other routes may involve the alkynylation of appropriate precursors. As a supplier, we focus on efficient and scalable production methods to ensure consistent availability and high purity of 7-Octyn-1-ol for our clients. Our manufacturing processes are optimized to deliver a product with excellent chemical integrity, crucial for its downstream applications.

Applications in Organic Synthesis:

  • Natural Product Synthesis: The precise carbon chain and reactive functional groups of 7-Octyn-1-ol make it an ideal intermediate in the total synthesis of complex natural products. For example, it has been utilized in building the carbon skeletons of sulfur-containing heterocyclic fatty acids and as a key component in the stereoselective synthesis of alkaloids like swainsonine.
  • Pheromone Synthesis: 7-Octyn-1-ol is a vital precursor in the synthesis of insect sex pheromones, such as those used to control pests like the citrus leafminer. Its structure allows for the controlled assembly of the long-chain unsaturated aldehydes that constitute these pheromones.
  • Building Block for Complex Molecules: The terminal alkyne can be readily transformed via various coupling reactions (e.g., Sonogashira coupling) to extend the carbon chain or introduce aromatic moieties. The alcohol group provides another handle for functionalization, allowing for the construction of intricate molecular architectures required in advanced organic synthesis.
  • Click Chemistry Applications: As mentioned previously, the terminal alkyne is a perfect partner for click chemistry, enabling efficient bioconjugation, materials functionalization, and the creation of diverse molecular libraries for drug discovery.

Why Purchase 7-Octyn-1-ol from Us?

Sourcing high-quality 7-Octyn-1-ol (CAS: 871-91-0) is critical for achieving reproducible and successful organic synthesis results. Our company is a reliable manufacturer and supplier dedicated to providing exceptional purity and consistent product quality. We offer competitive prices and flexible packaging options, supporting your research needs from small-scale experiments to larger production runs. When you need to buy this versatile organic intermediate, trust our expertise and commitment to excellence.