In the complex landscape of pharmaceutical manufacturing, sourcing high-quality building blocks is fundamental to successful drug development and production. 1,4-Dioxaspiro[4.5]decan-8-one (CAS 4746-97-8) has emerged as a key intermediate, valued for its structural features that lend themselves to the synthesis of various therapeutic compounds, most notably analgesics. Understanding its chemical profile and the advantages of sourcing it from reliable suppliers is crucial for R&D scientists and procurement specialists.

Chemical Profile of 1,4-Dioxaspiro[4.5]decan-8-one

This compound, identified by CAS number 4746-97-8, is often known by its synonym, 1,4-Cyclohexanedione monoethylene acetal. It typically presents as a white to beige crystalline powder or crystals, with a reported melting point range of 70-73 °C. Its molecular formula is C8H12O3, and it is soluble in common organic solvents such as chloroform and methanol. These properties make it a practical and versatile reactant in various chemical processes.

Applications Driving its Importance

The primary driver for the demand of 1,4-Dioxaspiro[4.5]decan-8-one is its role in the synthesis of potent analgesic compounds. Its structure allows for efficient incorporation into complex molecular frameworks designed to interact with specific biological targets. Additionally, it serves as a foundational element in the creation of tritium-labeled probes for autoradiography studies, aiding neurochemical research by helping scientists understand the dopamine reuptake complex. The compound's utility is further demonstrated in its application in advanced synthetic techniques like microwave-assisted reductive amination and aromatization, enabling the formation of serotonin and melatonin derivatives.

Strategic Procurement: Buying from Chinese Manufacturers

For organizations aiming to buy 1,4-Dioxaspiro[4.5]decan-8-one, exploring the market for chemical suppliers in China offers significant benefits. Chinese manufacturers often provide competitive pricing and a robust supply chain for fine chemical intermediates. When you purchase 1,4-Dioxaspiro[4.5]decan-8-one, it's imperative to select a supplier that guarantees high purity (typically >98%) and offers reliable delivery. Companies committed to quality and customer service, such as NINGBO INNO PHARMCHEM CO.,LTD., can provide the necessary support and ensure that you obtain this vital building block efficiently. Always inquire about specifications and pricing to make an informed decision.

In summary, 1,4-Dioxaspiro[4.5]decan-8-one is a critical intermediate for pharmaceutical innovation. By understanding its properties and leveraging the capabilities of expert Chinese manufacturers, your organization can secure a high-quality supply for your research and production needs.