For pharmaceutical manufacturers, the consistent and reliable supply of high-quality intermediates is paramount. 1,4-Dioxaspiro[4.5]decan-8-one (CAS 4746-97-8) stands out as a crucial building block in the synthesis of various important compounds, particularly those with analgesic properties. Understanding its characteristics and sourcing effectively can significantly impact your production efficiency and product quality.

Understanding 1,4-Dioxaspiro[4.5]decan-8-one

This fine chemical, often referred to by synonyms such as 1,4-Cyclohexanedione monoethylene acetal, is recognized for its unique spirocyclic structure. It typically presents as a white to beige crystalline powder or crystals, with a melting point range of 70-73 °C. Its solubility in common organic solvents like chloroform and methanol makes it amenable to various reaction conditions. The molecular formula is C8H12O3, and its CAS number is 4746-97-8.

Key Applications in Pharmaceutical Synthesis

The primary utility of 1,4-Dioxaspiro[4.5]decan-8-one lies in its role as an intermediate for potent analgesic compounds. Furthermore, it serves as a valuable building block in more specialized research, such as the synthesis of tritium-labeled probes for studying the dopamine reuptake complex. Its versatility extends to advanced organic synthesis techniques like microwave-assisted reductive amination and aromatization processes, leading to the formation of diverse amine derivatives.

Strategic Sourcing from China

When sourcing this critical intermediate, looking to established manufacturers and suppliers in China offers significant advantages, including competitive pricing and a broad range of supply capabilities. When you buy 1,4-Dioxaspiro[4.5]decan-8-one, it's essential to partner with a supplier who guarantees purity and reliable delivery. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on providing high-quality pharmaceutical intermediates, ensuring your procurement process is streamlined and efficient. Investigating supplier credentials, checking for certifications, and requesting samples are crucial steps before committing to a bulk purchase. Understanding the price points from various manufacturers will also help in optimizing your budget.

In summary, for pharmaceutical manufacturers seeking a robust supply of 1,4-Dioxaspiro[4.5]decan-8-one, diligent research into its properties and strategic sourcing from reputable Chinese suppliers are key to successful integration into your production workflow. This approach ensures you leverage this versatile chemical intermediate effectively.