Understanding the fundamental chemical properties and synthesis utility of key organic compounds is crucial for researchers and developers in the chemical industry. 1-Bromo-3,4-dichlorobenzene (CAS 18282-59-2) is a prime example of such a compound, serving as a versatile intermediate in numerous synthetic pathways. This article explores its characteristic properties and highlights why it is a sought-after building block for advanced chemical applications.

Key Chemical and Physical Properties

1-Bromo-3,4-dichlorobenzene, identified by CAS number 18282-59-2, is a halogenated aromatic compound with the molecular formula C6H3BrCl2. It typically presents as a clear to slightly yellow liquid. Its physical state is influenced by its melting point, which falls between 23-24°C, meaning it can solidify at cooler ambient temperatures. The boiling point is noted at approximately 124°C under reduced pressure (33 mmHg), and its density is around 1.761 g/mL at 25°C. The molecule's structure, featuring a bromine atom and two chlorine atoms on a benzene ring, dictates its reactivity and utility in synthesis. For those looking to buy 1-Bromo-3,4-dichlorobenzene, these properties are essential for process design and handling.

Synthesis Utility and Applications

The strategic positioning of the halogen atoms on the benzene ring makes 1-Bromo-3,4-dichlorobenzene a highly valuable intermediate in organic synthesis. Its primary utility lies in its role as a precursor for more complex molecules. Notably, it is frequently used in the synthesis of N-arylated sultams, a class of compounds that have garnered significant attention in medicinal chemistry and materials science for their unique biological and physical properties. The bromine atom provides a reactive site for various coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings, enabling the efficient construction of carbon-carbon and carbon-heteroatom bonds.

As a reliable aryl halide manufacturer, we understand the importance of consistent quality. When you procure this compound, you are acquiring a fundamental building block for pharmaceutical intermediates, agrochemicals, and specialty materials. The purity of the compound, typically 98% or higher, directly influences the success and efficiency of these downstream applications. Therefore, sourcing from a reputable chemical synthesis intermediate supplier is paramount.

Sourcing and Quality Assurance

For R&D scientists and purchasing managers, identifying a trustworthy supplier in China or elsewhere for 1-Bromo-3,4-dichlorobenzene (CAS 18282-59-2) is key. Ensuring that the product meets the required purity standards, often verified by GC analysis, is critical. Understanding the market price of 1-Bromo-3,4-dichlorobenzene involves comparing offers from multiple suppliers, but quality should always be the primary consideration. A well-documented product with a Certificate of Analysis (CoA) provides assurance of its specifications.

1-Bromo-3,4-dichlorobenzene’s distinctive chemical properties make it an indispensable tool in the repertoire of organic chemists. Its utility in constructing complex molecular architectures underscores its importance in advancing research and development across various scientific disciplines.