In the realm of fine chemicals, intermediates play a pivotal role in the synthesis of a vast array of complex molecules used in industries ranging from pharmaceuticals and agrochemicals to advanced materials. 2,2'-Dibromodiethyl Ether, known by its CAS number 5414-19-7, stands out as a highly versatile and valuable intermediate. Its bifunctional nature and specific reactivity make it an indispensable tool for chemists seeking to build intricate molecular architectures.

Chemical Profile of 2,2'-Dibromodiethyl Ether
2,2'-Dibromodiethyl Ether is an organic compound with the molecular formula C4H8Br2O and a molecular weight of 231.914. It is characterized as a colorless to slightly colored liquid, possessing a density of approximately 1.845 g/mL and a boiling point in the range of 92-93°C at 12 mmHg. The molecule features two terminal bromine atoms attached to ethyl groups, which are linked by an ether oxygen. This structural arrangement imparts a significant degree of reactivity, particularly in nucleophilic substitution reactions, making it an ideal electrophilic building block for synthetic chemists.

Synthetic Applications of 2,2'-Dibromodiethyl Ether
The versatility of 2,2'-Dibromodiethyl Ether allows for its application in numerous synthetic pathways:

  • Building Block for Substituted Ethers: Its primary use is as an intermediate for synthesizing various substituted diethyl ethers, which can form the core structure of many complex organic molecules.
  • Synthesis of Heterocycles: The two reactive bromine atoms facilitate cyclization reactions, leading to the formation of diverse heterocyclic compounds. These structures are prevalent in pharmaceuticals, agrochemicals, and specialty materials.
  • Crown Ether Synthesis: It is an important precursor in the preparation of crown ethers, macrocyclic polyethers known for their ability to selectively bind metal cations. This property makes them useful in areas like phase-transfer catalysis and ion sensing.
  • Pharmaceutical Intermediates: Its utility extends to the pharmaceutical sector, where it serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other drug candidates. Researchers leverage its reactivity to introduce specific functional groups and build complex molecular scaffolds.
  • Materials Science: In advanced materials research, it has been employed in synthesizing specialized molecules for applications such as photosensitizers used in photodynamic therapy (PDT).

Procurement and Supply Chain Considerations
For businesses and researchers requiring 2,2'-Dibromodiethyl Ether, sourcing from reliable manufacturers is crucial. Companies like NINGBO INNO PHARMCHEM CO.,LTD., a leading chemical manufacturer based in China, offer this intermediate with guaranteed quality and purity (often ≥95% or ≥99% by GC). When you decide to buy, it is advisable to obtain detailed product specifications, inquire about pricing for bulk orders, and confirm lead times to ensure your project timelines are met. Working with established suppliers ensures consistent quality and dependable supply chains.

The broad applicability of 2,2'-Dibromodiethyl Ether in fine chemical synthesis underscores its significance as a versatile intermediate, contributing to innovation across multiple scientific and industrial sectors.