In the intricate world of organic synthesis, certain molecules stand out for their versatility and importance as building blocks. 2,2'-Dibromodiethyl Ether, a compound with CAS number 5414-19-7, is one such molecule. Valued for its bifunctional nature, it plays a significant role in creating a wide array of complex organic structures, including pharmaceuticals, advanced materials, and specialized reagents. Understanding its synthesis and applications is key for R&D scientists and chemists looking to source this essential intermediate.

Synthesis and Chemical Properties
2,2'-Dibromodiethyl Ether, chemically known as 1-bromo-2-(2-bromoethoxy)ethane, possesses the molecular formula C4H8Br2O and a molecular weight of 231.914. It is characterized as a colorless transparent liquid with a density of 1.845 g/mL at 25°C and a boiling point of 92-93°C at 12 mmHg. The presence of two bromine atoms makes it highly reactive in nucleophilic substitution reactions. This reactivity is fundamental to its utility as an intermediate. Synthetically, it can be prepared from diethylene glycol using reagents like phosphorus tribromide in carbon tetrachloride, followed by purification steps to yield the desired product.

Applications Driving Innovation
The utility of 2,2'-Dibromodiethyl Ether spans several advanced fields:

  • Substituted Diethyl Ethers: It is a primary intermediate for synthesizing various substituted diethyl ether products, forming the backbone for many complex organic molecules.
  • Heterocyclic and Crown Ether Synthesis: Its structure makes it ideal for cyclization reactions, leading to the formation of heterocyclic compounds and macrocyclic polyethers like crown ethers. These are vital in areas such as host-guest chemistry and phase-transfer catalysis.
  • Porphyrazine and Porphyrin Derivatives: Researchers have utilized 2,2'-Dibromodiethyl Ether in synthesizing specialized porphyrinoid macrocycles. These compounds have potential applications in photodynamic diagnosis (PDD) and photodynamic therapy (PDT) due to their unique photophysical properties, such as generating singlet oxygen upon light irradiation.
  • Pharmaceutical Intermediates: Its reactive bromine atoms allow for facile functionalization, making it a valuable starting material or intermediate in the synthesis of pharmaceutical compounds, including certain antiviral agents and other bioactive molecules.

Sourcing High-Quality 2,2'-Dibromodiethyl Ether
For researchers and chemical manufacturers, securing a reliable supply of high-purity 2,2'-Dibromodiethyl Ether is essential. When looking to buy this compound, it is important to partner with manufacturers who can guarantee consistent quality and purity. Manufacturers in China, like NINGBO INNO PHARMCHEM CO.,LTD., are significant suppliers of such intermediates, offering competitive pricing and bulk availability. Ensuring the supplier provides detailed specifications and reliable lead times will facilitate smoother research and production workflows.

The versatility of 2,2'-Dibromodiethyl Ether makes it an indispensable tool in the arsenal of organic chemists. Its role in creating complex structures with specific functionalities continues to drive innovation across multiple scientific disciplines.