2-Hexylthiophene: A Versatile Intermediate in Pharmaceutical Synthesis
The pharmaceutical industry constantly seeks efficient and reliable chemical intermediates to develop new and improved therapeutic agents. Among the diverse range of organic compounds utilized, heterocyclic molecules, particularly those containing sulfur, play a significant role. 2-Hexylthiophene, with its CAS number 18794-77-9, stands out as a versatile and important intermediate in pharmaceutical synthesis. This article explores its chemical properties, applications, and why it is a preferred choice for many drug development processes.
2-Hexylthiophene is a functionalized thiophene derivative, possessing the molecular formula C10H16S and a molecular weight of approximately 168.30 g/mol. Its structure, featuring a hexyl chain attached to the thiophene ring, provides a unique chemical scaffold that can be manipulated through various organic reactions. The compound is typically a light yellow liquid with a boiling point of around 228-230°C. Its stability under normal temperatures and pressures, coupled with a purity level of 95% or higher, makes it an attractive component for complex multi-step syntheses common in the pharmaceutical sector.
The utility of 2-Hexylthiophene as a pharmaceutical intermediate stems from its reactivity and the diverse range of transformations it can undergo. It serves as a precursor for a variety of bioactive molecules, enabling the introduction of the thiophene moiety into larger drug structures. The thiophene ring system is frequently found in pharmaceuticals due to its ability to engage in pi-pi stacking interactions and its favorable metabolic profile. For companies focused on drug discovery and development, securing a consistent supply of high-quality pharmaceutical intermediates like 2-Hexylthiophene from reputable manufacturers in China is crucial.
Researchers can utilize 2-Hexylthiophene in various synthetic strategies, including palladium-catalyzed cross-coupling reactions (such as Suzuki, Stille, or Heck couplings) to attach other functional groups or molecular fragments. This allows for the construction of complex molecular architectures essential for creating novel drug candidates. The ability to precisely control the introduction of the hexylthiophene unit enhances the selectivity and yield of these critical synthetic steps.
In essence, 2-Hexylthiophene is more than just a chemical compound; it is a key enabler in the journey from laboratory research to commercial pharmaceutical production. Its role as a reliable building block empowers chemists to synthesize innovative medicines that address unmet medical needs. For manufacturers seeking to optimize their synthesis of drug candidates, partnering with suppliers who offer this vital intermediate is a fundamental step towards success.
2-Hexylthiophene is a functionalized thiophene derivative, possessing the molecular formula C10H16S and a molecular weight of approximately 168.30 g/mol. Its structure, featuring a hexyl chain attached to the thiophene ring, provides a unique chemical scaffold that can be manipulated through various organic reactions. The compound is typically a light yellow liquid with a boiling point of around 228-230°C. Its stability under normal temperatures and pressures, coupled with a purity level of 95% or higher, makes it an attractive component for complex multi-step syntheses common in the pharmaceutical sector.
The utility of 2-Hexylthiophene as a pharmaceutical intermediate stems from its reactivity and the diverse range of transformations it can undergo. It serves as a precursor for a variety of bioactive molecules, enabling the introduction of the thiophene moiety into larger drug structures. The thiophene ring system is frequently found in pharmaceuticals due to its ability to engage in pi-pi stacking interactions and its favorable metabolic profile. For companies focused on drug discovery and development, securing a consistent supply of high-quality pharmaceutical intermediates like 2-Hexylthiophene from reputable manufacturers in China is crucial.
Researchers can utilize 2-Hexylthiophene in various synthetic strategies, including palladium-catalyzed cross-coupling reactions (such as Suzuki, Stille, or Heck couplings) to attach other functional groups or molecular fragments. This allows for the construction of complex molecular architectures essential for creating novel drug candidates. The ability to precisely control the introduction of the hexylthiophene unit enhances the selectivity and yield of these critical synthetic steps.
In essence, 2-Hexylthiophene is more than just a chemical compound; it is a key enabler in the journey from laboratory research to commercial pharmaceutical production. Its role as a reliable building block empowers chemists to synthesize innovative medicines that address unmet medical needs. For manufacturers seeking to optimize their synthesis of drug candidates, partnering with suppliers who offer this vital intermediate is a fundamental step towards success.
Perspectives & Insights
Silicon Analyst 88
“For companies focused on drug discovery and development, securing a consistent supply of high-quality pharmaceutical intermediates like 2-Hexylthiophene from reputable manufacturers in China is crucial.”
Quantum Seeker Pro
“Researchers can utilize 2-Hexylthiophene in various synthetic strategies, including palladium-catalyzed cross-coupling reactions (such as Suzuki, Stille, or Heck couplings) to attach other functional groups or molecular fragments.”
Bio Reader 7
“This allows for the construction of complex molecular architectures essential for creating novel drug candidates.”