In the realm of advanced chemistry, fluorinated organic compounds hold a special place due to the unique properties conferred by the fluorine atom. These properties often translate to enhanced stability, altered reactivity, and improved biological activity in molecules. For chemists and formulators, sourcing specific fluorinated intermediates is crucial for innovation. 1-Bromo-4-fluorobutane (CAS: 462-72-6) is a prime example of a valuable fluorinated building block, offering a gateway to a wide range of applications.

Why Fluorinated Compounds Matter

The incorporation of fluorine into organic molecules can dramatically influence their physical, chemical, and biological characteristics. This includes:

  • Increased Lipophilicity: Enhancing cell membrane permeability, crucial for drug delivery.
  • Altered Electronic Properties: Affecting acidity, basicity, and reaction rates.
  • Enhanced Metabolic Stability: The strong carbon-fluorine bond is resistant to enzymatic cleavage, extending the half-life of pharmaceuticals or agrochemicals.
  • Unique Steric and Electronic Effects: Influencing molecular conformation and binding affinities.

These advantages make fluorinated compounds highly sought after in pharmaceuticals, agrochemicals, advanced materials, and specialty chemicals. Therefore, securing a reliable supply of intermediates like 1-Bromo-4-fluorobutane is a strategic imperative for companies aiming for product differentiation and performance enhancement.

1-Bromo-4-fluorobutane: A Dual-Functionality Asset

1-Bromo-4-fluorobutane stands out as a useful intermediate because it combines the reactivity of an alkyl bromide with the unique properties of a terminal fluoride. The bromine atom serves as an excellent leaving group for nucleophilic substitution and a handle for cross-coupling reactions. The fluorine atom, on the other hand, offers the aforementioned benefits of fluorination and can often remain intact through various synthetic steps. This dual functionality makes it an efficient building block for creating complex fluorinated molecules.

Researchers and manufacturers looking to buy 1-bromo-4-fluorobutane leverage its structure for synthesizing compounds with tailored properties. For instance, it can be used to introduce a 4-fluorobutyl chain into active molecules, potentially improving their pharmacological profiles or stability.

Sourcing Strategies for Fluorinated Intermediates

When seeking to purchase 1-bromo-4-fluorobutane, it’s vital to partner with suppliers who specialize in fine chemicals and intermediates, particularly those with expertise in halogenated compounds. Identifying a reputable CAS 462-72-6 supplier, such as a dedicated chemical manufacturer in China, can provide access to high-purity materials at competitive price points. Prioritizing suppliers who can offer consistent quality, reliable delivery, and comprehensive technical documentation (like COAs) is paramount. Exploring the 1-bromo-4-fluorobutane price from various manufacturers will help in making an informed purchasing decision for laboratory or industrial needs.

By understanding the value of fluorinated intermediates and strategically sourcing compounds like 1-Bromo-4-fluorobutane, chemical industries can continue to drive innovation and develop next-generation products.