The pharmaceutical industry constantly seeks novel and efficient synthetic routes to develop life-saving drugs. Within this landscape, specific chemical intermediates play pivotal roles as building blocks. 1-Bromo-4-fluorobutane (CAS: 462-72-6) stands out as one such crucial compound, widely employed in the synthesis of various Active Pharmaceutical Ingredients (APIs) and drug candidates. Understanding its applications and reliable sourcing is key for R&D scientists and production chemists.

1-Bromo-4-fluorobutane: A Versatile Building Block

1-Bromo-4-fluorobutane is valued for its bifunctional nature, featuring both a bromine and a fluorine atom on a four-carbon chain. This dual functionality allows for selective reactions, such as nucleophilic substitutions or Grignard reagent formation, enabling chemists to incorporate specific structural motifs into larger molecules. Its utility spans various therapeutic areas, contributing to the creation of complex organic molecules essential for modern medicine.

Applications in Drug Discovery and Development

Researchers often look to buy 1-bromo-4-fluorobutane for its direct application in synthesizing intermediates for:

  • Anticancer Agents: Specific structural fragments derived from 1-Bromo-4-fluorobutane can be crucial for the efficacy of certain chemotherapy drugs.
  • Neurological Drugs: Its incorporation into molecular structures can influence receptor binding and therapeutic activity in treatments for neurological disorders.
  • Cardiovascular Medications: The compound can serve as a precursor for building complex molecules targeting cardiovascular diseases.

The ability to easily functionalize either the bromo or fluoro end makes it an attractive starting material for multi-step syntheses. When sourcing for these critical applications, the purity of the material is paramount. High-purity 1-bromo-4-fluorobutane ensures predictable reaction outcomes and minimizes the formation of unwanted byproducts, a critical factor in pharmaceutical manufacturing.

Sourcing High-Quality 1-Bromo-4-fluorobutane

For pharmaceutical companies, identifying a dependable 1-bromo-4-fluorobutane manufacturer is essential. Suppliers like NINGBO INNO PHARMCHEM CO.,LTD. are known for providing materials with stringent quality control, typically offering assays of ≥99.0% purity. This commitment to quality is vital for meeting regulatory requirements and ensuring the safety and efficacy of the final drug products. Procurement managers should always prioritize suppliers who can provide comprehensive documentation, including COAs and lot traceability.

When seeking to purchase 1-bromo-4-fluorobutane, it's advisable to contact suppliers directly to discuss project-specific needs. Understanding the CAS 462-72-6 supplier landscape, including competitive 1-bromo-4-fluorobutane price points and lead times, will facilitate efficient procurement. Exploring options for contract manufacturing or custom synthesis can also be beneficial for specific pharmaceutical development projects requiring unique specifications or quantities.

By prioritizing quality and reliability in sourcing this key intermediate, pharmaceutical innovators can accelerate their drug development pipelines and bring vital new therapies to market faster.