The formation of amide bonds is a fundamental transformation in organic chemistry, critical for synthesizing a vast array of compounds, from pharmaceuticals and agrochemicals to polymers and fine chemicals. Among the most effective and widely used reagents for achieving this transformation is EDC HCl (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride). As a reputable manufacturer of EDC HCl, we are dedicated to providing chemists and procurement specialists with a reliable source for this indispensable coupling agent.

EDC HCl's efficacy in amide synthesis stems from its ability to activate carboxylic acids. In a typical reaction, the carboxylic acid reacts with EDC HCl to form an unstable O-acylisourea intermediate. This highly reactive species is then readily attacked by an amine nucleophile, leading to the formation of a stable amide bond and the release of a urea byproduct. What sets EDC HCl apart, especially when you buy EDC HCl from a trusted supplier, is that this urea byproduct is water-soluble. This property is a significant advantage over reagents like DCC, whose insoluble dicyclohexylurea byproduct can complicate product isolation and purification.

The versatility of EDC HCl extends to its use in various reaction conditions. It is soluble in many common organic solvents such as dichloromethane (DCM), dimethylformamide (DMF), and tetrahydrofuran (THF), as well as in water. This broad solubility profile allows chemists to select the optimal reaction medium for their specific synthesis. Furthermore, EDC HCl is frequently employed in combination with additives like N-hydroxysuccinimide (NHS) or hydroxybenzotriazole (HOBt) to further enhance reaction rates and minimize potential side reactions, such as racemization, which is particularly important in the synthesis of chiral molecules.

For procurement managers and research scientists, securing a consistent supply of high-purity EDC HCl is crucial for reproducible results. Our company, as a leading supplier of EDC HCl in China, ensures that our product meets rigorous quality standards. We understand that the EDC HCl price is a key consideration, and we strive to offer competitive pricing, especially for bulk purchases, making it an accessible reagent for both research and industrial-scale synthesis.

Whether you are developing new pharmaceutical candidates, synthesizing advanced materials, or exploring novel chemical pathways, relying on a quality source for your coupling reagents is paramount. By choosing us as your supplier of 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, you are investing in a reagent that streamlines amide synthesis, simplifies purification, and supports your innovation. We invite you to inquire about our product specifications and place your order for EDC HCl today to experience the benefits of working with a dedicated chemical manufacturer.