For researchers and procurement managers in the pharmaceutical and biotechnology sectors, the efficiency and purity of peptide synthesis are paramount. A key reagent that enables success in this complex field is 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, commonly known as EDC HCl. As a premier supplier of EDC HCl, we understand its critical role in achieving high-quality peptide chains.

EDC HCl functions as a highly effective coupling agent, primarily facilitating the formation of amide bonds between a carboxylic acid group and an amine group. This reaction is the fundamental building block of peptides. Unlike older carbodiimide reagents such as DCC, EDC HCl offers a significant advantage: its urea byproduct is water-soluble. This characteristic drastically simplifies the purification process, as the byproduct can be easily removed through aqueous extraction, a critical factor for obtaining the high purity required in pharmaceutical applications. This makes our EDC HCl for peptide synthesis a preferred choice for many R&D laboratories.

The mechanism involves the activation of the carboxylic acid group to form a reactive O-acylisourea intermediate. This intermediate is then readily attacked by an amine, forming the desired amide bond. To further enhance efficiency and minimize racemization – a common challenge in peptide synthesis, particularly with sensitive amino acids – EDC HCl is often used in conjunction with additives like N-hydroxysuccinimide (NHS) or 1-hydroxybenzotriazole (HOBt). These additives form activated esters that couple more cleanly with amines.

The demand for reliable peptide-based therapeutics and diagnostics continues to grow, underscoring the need for dependable sources of high-quality reagents. As a leading manufacturer of EDC HCl in China, we are committed to providing a consistent supply of this essential chemical. Whether you are scaling up production or conducting cutting-edge research, understanding how to effectively buy EDC HCl can significantly impact your project's success. Our product ensures excellent solubility in both aqueous and organic solvents, offering flexibility in reaction design.

For procurement managers, sourcing critical reagents like EDC HCl involves balancing cost, quality, and reliability. We offer competitive EDC HCl price points, especially for bulk purchases, without compromising on the stringent purity standards required by the industry. By choosing us as your supplier of 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, you gain access to a product that facilitates efficient peptide synthesis and a partner dedicated to supporting your scientific endeavors. Contact us today to discuss your needs and learn more about how our EDC HCl can benefit your operations.