3-Formylpyridine, commonly known as 3-Pyridinecarboxaldehyde (CAS 500-22-1) or nicotinaldehyde, is a compound of significant interest in the field of organic chemistry. As a clear yellow to light brown liquid, it possesses unique chemical properties that make it a sought-after intermediate in numerous industrial applications, ranging from pharmaceuticals to agrochemicals and beyond.

Delving into the chemical properties of 3-formylpyridine reveals its reactive aldehyde group and the pyridine ring structure, which contribute to its versatility. This reactivity allows it to participate in a wide array of chemical transformations, making it an excellent starting material for synthesizing more complex molecules. Its known reactivity with amines, alcohols, and hydrazines is particularly valuable in the development of new chemical entities.

The primary industrial applications of 3-Pyridinecarboxaldehyde are concentrated in two major sectors: pharmaceuticals and agrochemicals. As a pharmaceutical intermediate, it is employed in the synthesis of various active pharmaceutical ingredients (APIs), including compounds with potential therapeutic benefits such as anti-inflammatory and anti-cancer properties. The compound's connection to niacin activity further enhances its relevance in developing related compounds and nutritional supplements.

In the agrochemical industry, 3-formylpyridine serves as a critical intermediate for creating effective crop protection agents. Its role in the synthesis of pesticide intermediates and other agricultural chemicals is vital for ensuring crop health and improving agricultural output. Reliable access to this compound through reputable 3-Pyridinecarboxaldehyde suppliers is essential for ongoing research and production.

Furthermore, the compound has a unique characteristic of being a component of tobacco smoke, highlighting its presence in the tobacco industry. This specific application, while distinct from its synthetic roles, points to the broad spectrum of its chemical behavior.

For effective utilization and storage, understanding the handling requirements of 3-Pyridinecarboxaldehyde is important. It is typically stored at refrigeration temperatures (2-8°C) and is noted for its air sensitivity, necessitating careful handling to maintain its chemical integrity.

The CAS number 500-22-1 uniquely identifies this compound, facilitating its traceability and procurement. As research and industrial applications continue to evolve, the demand for high-quality 3-Pyridinecarboxaldehyde remains strong, underscoring its enduring importance as a fundamental building block in modern chemical synthesis and product development.