In the realm of synthetic chemistry, understanding the detailed properties and potential applications of key intermediates is crucial for innovation. 5-Bromo-2-chloroisonicotinaldehyde, identified by its CAS number 1060802-23-4, is a compound of significant interest due to its versatile chemical nature and diverse applications in organic synthesis and pharmaceutical research.

Chemical Profile: Structure and Properties

5-Bromo-2-chloroisonicotinaldehyde is a halogenated pyridine aldehyde with the molecular formula C6H3BrClNO and a molecular weight of 220.45 g/mol. Its structure comprises a pyridine ring substituted with a bromine atom at the 5-position, a chlorine atom at the 2-position, and a formyl (aldehyde) group at the 4-position of the pyridine ring. Typically supplied with a purity of 97% or higher, this compound exhibits properties that make it an excellent building block for more complex molecular structures.

Physically, it is often described as a pale yellow solid. Its chemical reactivity is dominated by the aldehyde group, which readily undergoes nucleophilic addition reactions, and the halogen substituents, which can participate in nucleophilic substitution and various cross-coupling reactions. These reactive sites allow chemists to introduce a wide array of functional groups, tailoring the molecule for specific applications.

Synthesis and Reaction Mechanisms

The synthesis of 5-Bromo-2-chloroisonicotinaldehyde typically involves directed halogenation of pyridine precursors. Reaction conditions must be carefully controlled to achieve regioselectivity and good yields. Common synthetic routes might involve bromination and chlorination steps on an appropriately substituted pyridine aldehyde or its precursor. Understanding these synthesis pathways is essential for both production and quality control when sourcing from a manufacturer.

The compound's utility in organic synthesis is vast. For example, the aldehyde group can be converted into alcohols, amines, or carboxylic acids. The halogen atoms can be displaced by nucleophiles or used in metal-catalyzed coupling reactions to form carbon-carbon or carbon-heteroatom bonds. These transformations are fundamental in building the intricate molecular architectures required for pharmaceuticals and advanced materials.

Applications and Sourcing Insights

As a key pharmaceutical intermediate, 5-Bromo-2-chloroisonicotinaldehyde aids in the synthesis of potential drug candidates. Its structure provides a scaffold that can be elaborated to target various biological pathways. Beyond pharmaceuticals, it finds use in the development of agrochemicals and specialty chemicals. When looking to buy 5-Bromo-2-chloroisonicotinaldehyde, it is imperative to partner with a reputable supplier that can guarantee quality and consistency.

For B2B purchasers, understanding the market dynamics is crucial. Obtaining a competitive quote from a trusted 5-Bromo-2-chloroisonicotinaldehyde supplier in China can offer significant cost advantages. We, as experienced chemical providers, are committed to supplying high-quality intermediates. We encourage you to inquire about our product specifications and to discuss your requirements for this valuable chemical building block.

In summary, 5-Bromo-2-chloroisonicotinaldehyde (CAS 1060802-23-4) is a compound with significant chemical utility, essential for various advanced synthesis applications. Careful sourcing from reliable manufacturers ensures access to high-purity materials, facilitating innovation in the chemical and pharmaceutical industries.