NINGBO INNO PHARMCHEM CO.,LTD is dedicated to providing comprehensive information on the chemical intermediates we supply, including 2-Bromophenanthrene (CAS 62162-97-4). Understanding its chemical properties and how it is synthesized is crucial for its effective utilization in organic synthesis, OLED material development, and pharmaceutical intermediate production.

2-Bromophenanthrene, with the molecular formula C14H9Br and a molecular weight of 257.129 g/mol, is characterized by a phenanthrene ring system substituted with a bromine atom at the 2-position. This specific structure imparts distinct reactivity. The phenanthrene core is an aromatic polycyclic hydrocarbon, contributing to its stability and electronic properties. The bromine atom, being an electronegative halogen, activates the adjacent carbon atoms and serves as a good leaving group in various substitution and coupling reactions. Its melting point typically ranges from 95-99°C, and it appears as a white powder, indicative of its purity.

The synthesis of 2-Bromophenanthrene often involves the electrophilic bromination of phenanthrene. Phenanthrene itself can be obtained from coal tar or synthesized through various cyclization reactions. The bromination reaction typically uses a brominating agent, such as elemental bromine (Br2) or N-bromosuccinimide (NBS), often in the presence of a Lewis acid catalyst (e.g., FeBr3 or AlCl3) or under specific solvent conditions to direct the substitution to the desired 2-position. Achieving high regioselectivity for the 2-position can be a key challenge, and synthetic routes are often optimized to maximize the yield of the 2-isomer while minimizing other brominated products.

The reactive bromine atom makes 2-Bromophenanthrene a highly sought-after intermediate for cross-coupling reactions, such as the Suzuki-Miyaura coupling (with boronic acids), Stille coupling (with organotin reagents), or Heck reaction (with alkenes). These reactions are fundamental in constructing larger, more complex organic molecules used in OLED materials, pharmaceuticals, and other advanced chemical applications. The ability to efficiently buy 2-Bromophenanthrene from reliable sources ensures that these complex synthetic pathways can be reliably executed.

At NINGBO INNO PHARMCHEM CO.,LTD, we provide 2-Bromophenanthrene that meets high purity standards, ensuring its suitability for demanding synthetic applications. Our commitment to quality supports the advancements in organic chemistry and material science.