In the realm of scientific research and pharmaceutical development, the choice of buffer is paramount. Biological buffers are crucial for maintaining a stable pH environment, which is essential for the optimal function of enzymes, proteins, and cells. Among the widely recognized Good's buffers, MES Monohydrate (CAS 145224-94-8) stands out for its unique properties and diverse applications. As a leading manufacturer and supplier, we aim to provide clarity on why MES Monohydrate is a critical component for many laboratories and production facilities.

MES Monohydrate is a zwitterionic N-substituted aminosulfonic acid. This means it possesses both a positive and a negative charge within the same molecule, allowing it to act as an effective buffer over a specific pH range. Specifically, MES Monohydrate is known for its buffering capacity between pH 5.5 and 6.7, with a pKa of approximately 6.1 at 20°C. This range is highly relevant for many biological processes and chemical reactions that occur under slightly acidic to neutral conditions.

One of the key advantages of MES Monohydrate is its minimal interaction with biological macromolecules and metal ions. Unlike some other buffers, such as phosphates or acetates, MES does not readily form coordination complexes with many metal ions. This property makes it an excellent choice for experiments involving metal-sensitive systems or where precise ionic strength control is necessary. Furthermore, its low UV absorptivity makes it transparent in UV light, a critical feature for spectrophotometric assays where the buffer should not interfere with the measurement of target molecules.

The applications of MES Monohydrate are extensive. In biochemical research, it is widely used in enzyme assays, protein purification, and as a running buffer in gel electrophoresis for resolving small proteins. Its ability to maintain stable pH is vital for ensuring the activity and integrity of enzymes and proteins throughout an experiment. Beyond research, MES Monohydrate has applications in nanotechnology, where it can be used in the synthesis of nanoparticles. In the pharmaceutical industry, it serves as a valuable excipient, contributing to the stability and solubility of drug formulations, adhering to stringent quality standards like USP, BP, EP, and FCC.

When sourcing MES Monohydrate, it is crucial to partner with a reliable manufacturer and supplier. We pride ourselves on offering high-purity MES Monohydrate (≥99.5% assay), ensuring consistent quality and performance for your critical applications. Whether you are conducting cutting-edge research, developing novel pharmaceutical products, or working in nanotechnology, understanding the properties and applications of MES Monohydrate is key. We are committed to providing the necessary documentation and competitive pricing to support your procurement needs. If you are looking to buy MES Monohydrate or seeking a dependable MES Monohydrate supplier in China, our team is ready to assist you with your specific requirements.