For any B2B procurement professional, understanding the pricing dynamics of key chemical intermediates is crucial for effective budgeting and cost management. 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one (CAS 28230-32-2), a vital additive in peptide synthesis, is no exception. The price of this compound, sourced from manufacturers and suppliers, is influenced by several factors, primarily quantity, purity, and the supplier's operational costs.

As a specialized fine chemical intermediate, 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one is used to enhance the efficiency and fidelity of peptide synthesis. Its primary function is to minimize racemization, a common issue when coupling amino acids, particularly when using agents like DCC. By promoting cleaner reactions and higher yields, it ultimately contributes to a more cost-effective overall synthesis process, despite its own acquisition cost.

The most significant factor affecting the price of 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one is the purchase quantity. When buying in bulk – typically kilogram or ton quantities from manufacturers in China – the per-unit price is substantially lower compared to purchasing gram-scale amounts for laboratory research. This economies-of-scale principle is common across the chemical industry. Buyers looking for the best price often plan their procurement to align with larger order volumes.

Purity is another critical determinant of cost. Higher purity grades, often exceeding 98% or 99% as verified by analytical techniques like HPLC, command a higher price. This is because achieving these stringent purity levels requires more sophisticated purification processes, which add to the manufacturing cost. For most peptide synthesis applications, a high purity is essential to avoid introducing contaminants that could compromise the final peptide product. Therefore, balancing cost with the required purity is a key consideration for buyers.

When evaluating the price from different suppliers, it's important to consider more than just the quoted dollar amount. Factors such as the supplier's reputation, the reliability of their supply chain, their adherence to quality standards (e.g., ISO certification), and the terms of delivery (e.g., FOB, CIF) all contribute to the total cost of ownership. A slightly higher initial price from a trusted manufacturer might offer better long-term value through consistent quality and fewer production disruptions.

For businesses looking to purchase 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one, engaging directly with manufacturers and suppliers, especially those based in China, can provide clearer insights into pricing structures. Requesting detailed quotations that outline unit prices, minimum order quantities, and potential discounts for larger volumes is a standard practice. By understanding these elements, procurement teams can make informed decisions to secure this vital chemical intermediate at a competitive price, thereby optimizing their overall peptide synthesis operations.