Guanidine Thiocyanate: The Ultimate Chaotropic Agent for Nucleic Acid Extraction
In the intricate world of molecular biology and diagnostics, the purity and efficacy of reagents are paramount. Guanidine Thiocyanate (GTC), identified by CAS number 593-84-0, stands out as a cornerstone chemical, primarily recognized for its potent chaotropic properties. As a leading Guanidine Thiocyanate supplier in China, we understand the critical needs of researchers and manufacturers in securing high-quality materials for their vital work.
Guanidine Thiocyanate is a white crystalline powder that acts as a powerful protein denaturant. Its unique ability to disrupt hydrogen bonding networks in water molecules and interfere with protein structures makes it exceptionally effective in cell lysis and the subsequent extraction of nucleic acids, namely DNA and RNA. This compound is not merely a solvent; it's an active participant in breaking down cellular barriers and neutralizing enzymatic threats to your precious genetic material.
One of the most significant advantages of Guanidine Thiocyanate is its capacity to denature RNases and DNases. These ubiquitous enzymes are a constant challenge in molecular biology, as they can rapidly degrade RNA and DNA, leading to compromised yields and unreliable experimental results. By effectively denaturing these nucleases, Guanidine Thiocyanate safeguards the integrity of your nucleic acid samples, ensuring that your extracted DNA and RNA remain intact for downstream applications like PCR, sequencing, or gene expression analysis.
The process of extracting DNA and RNA often involves harsh chemical treatments. Guanidine Thiocyanate, when used in buffer formulations, effectively lyses cells and viruses, releasing their contents. This action, combined with its protein denaturing capabilities, simplifies the purification process, allowing for cleaner separation of nucleic acids from cellular debris and proteins. Many protocols for nucleic acid isolation, especially for sensitive applications, specify the use of high-purity Guanidine Thiocyanate to achieve optimal outcomes.
For procurement managers and research scientists, sourcing reliable and high-quality Guanidine Thiocyanate is a critical decision. As a dedicated manufacturer and supplier from China, we are committed to providing products that meet stringent quality standards. If you are looking to buy Guanidine Thiocyanate for your research or manufacturing needs, understanding the typical specifications—such as a melting point around 118-121°C and a purity of ≥99.5%—is key. We offer competitive Guanidine Thiocyanate price points, especially for bulk purchases, making it feasible to maintain a consistent supply for your laboratory or production line.
When considering a supplier for critical biochemicals like Guanidine Thiocyanate, factors such as product consistency, reliable delivery, and responsive customer service are vital. We pride ourselves on being a trusted source for Guanidine Thiocyanate, supporting scientific innovation across various sectors. Whether you are involved in molecular diagnostics, virology, or fundamental genetic research, our high-purity Guanidine Thiocyanate is engineered to meet your most demanding requirements. For inquiries about pricing, bulk orders, or to request a sample of our Guanidine Thiocyanate, please contact our sales team. Secure your supply chain with a reputable Guanidine Thiocyanate manufacturer.
Perspectives & Insights
Logic Thinker AI
“Whether you are involved in molecular diagnostics, virology, or fundamental genetic research, our high-purity Guanidine Thiocyanate is engineered to meet your most demanding requirements.”
Molecule Spark 2025
“For inquiries about pricing, bulk orders, or to request a sample of our Guanidine Thiocyanate, please contact our sales team.”
Alpha Pioneer 01
“In the intricate world of molecular biology and diagnostics, the purity and efficacy of reagents are paramount.”