In the intricate world of chemical synthesis, the availability of reliable and versatile intermediates is paramount for driving innovation and ensuring efficient production. Among these vital compounds, heterocyclic molecules play a significant role, and 4-Chloro-2,2'-bipyridine (CAS 14162-94-8) stands out as a key chemical intermediate widely utilized across various industries.

Understanding 4-Chloro-2,2'-bipyridine

4-Chloro-2,2'-bipyridine is a derivative of 2,2'-bipyridine, characterized by the presence of a chlorine atom at the 4-position of one of the pyridine rings. This structural feature imbues it with specific chemical properties that are highly valued in synthesis. Typically supplied as an off-white solid, its molecular formula is C₁₀H₇ClN₂, with a molecular weight of approximately 190.63 g/mol. The compound’s CAS number, 14162-94-8, ensures precise identification for sourcing and regulatory purposes.

Applications Driving Demand

The demand for 4-Chloro-2,2'-bipyridine is primarily driven by its crucial roles in two main areas:

  • Organic Synthesis: As an intermediate, it serves as a vital building block. The chlorine atom is a reactive site that can be readily functionalized through various chemical reactions, including nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions like Suzuki and Stille couplings. This allows chemists to construct more complex organic molecules, which are often precursors for pharmaceuticals, agrochemicals, and functional materials.
  • Coordination Chemistry: The 2,2'-bipyridine moiety is a well-known chelating ligand, capable of forming stable complexes with a wide range of metal ions. 4-Chloro-2,2'-bipyridine retains this ability, making it useful in the development of metal catalysts for organic transformations, in photochemistry, and in materials science for creating compounds with specific electronic or optical properties.

For researchers and product developers, having a consistent and high-quality source for this intermediate is essential for their project timelines and success.

Sourcing Strategies for B2B Buyers

When looking to purchase 4-Chloro-2,2'-bipyridine, B2B buyers should prioritize reliability, quality, and cost-effectiveness. Key steps for effective sourcing include:

  • Identifying Reputable Suppliers: Seek out chemical manufacturers and suppliers with established track records in providing specialty chemical intermediates. Many reliable suppliers operate from China, offering competitive pricing and robust production capacities.
  • Verifying Product Specifications: Always request detailed product information, including purity levels (typically ≥97%), CAS number, and any relevant analytical data such as Certificates of Analysis (CoA).
  • Obtaining Quotes and Negotiating Price: Engage with suppliers to get quotes for the required quantities. Understanding the price per unit (e.g., per kilogram) is crucial for budgeting.
  • Considering Lead Times and Logistics: For industrial applications, ensuring timely delivery is critical. Discuss lead times, packaging, and shipping options to meet your production schedules.

By strategically sourcing 4-Chloro-2,2'-bipyridine, companies can ensure they have access to this essential chemical intermediate, enabling them to advance their research, develop new products, and maintain efficient manufacturing operations.