Key Chemical Synthesis Building Block: 2-Bromo-4-(trifluoromethyl)benzonitrile
The success of modern chemical synthesis relies heavily on the availability of versatile and reactive building blocks. 2-Bromo-4-(trifluoromethyl)benzonitrile (CAS: 35764-15-9) exemplifies such a critical component, offering a unique combination of functionalities that are highly prized in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer based in China, is a key provider of this essential organic intermediate.
The structure of 2-Bromo-4-(trifluoromethyl)benzonitrile is key to its utility. It features a benzonitrile core, a trifluoromethyl group (–CF3), and a bromine atom. The nitrile group can be converted into various other functional groups, such as carboxylic acids, amides, or amines, providing significant synthetic flexibility. The trifluoromethyl group is renowned for its electron-withdrawing properties and its ability to enhance lipophilicity and metabolic stability in the final molecular product. This makes it particularly valuable in the design of drug candidates and pesticides.
Furthermore, the bromine atom acts as an excellent handle for a wide array of metal-catalyzed cross-coupling reactions. Techniques like Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling allow chemists to efficiently forge new carbon-carbon bonds, enabling the construction of complex molecular architectures. This makes 2-Bromo-4-(trifluoromethyl)benzonitrile an indispensable tool for researchers aiming to develop novel compounds with specific biological or material properties. The ability to buy this chemical from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures that these sophisticated syntheses can be carried out with confidence.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality chemical synthesis building blocks, including 2-Bromo-4-(trifluoromethyl)benzonitrile, to the global market. Our commitment to purity, consistency, and competitive pricing makes us a preferred partner for innovation in the pharmaceutical and agrochemical sectors. By providing this key intermediate, we empower scientists and manufacturers to push the boundaries of chemical synthesis and bring life-changing products to fruition.
The structure of 2-Bromo-4-(trifluoromethyl)benzonitrile is key to its utility. It features a benzonitrile core, a trifluoromethyl group (–CF3), and a bromine atom. The nitrile group can be converted into various other functional groups, such as carboxylic acids, amides, or amines, providing significant synthetic flexibility. The trifluoromethyl group is renowned for its electron-withdrawing properties and its ability to enhance lipophilicity and metabolic stability in the final molecular product. This makes it particularly valuable in the design of drug candidates and pesticides.
Furthermore, the bromine atom acts as an excellent handle for a wide array of metal-catalyzed cross-coupling reactions. Techniques like Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling allow chemists to efficiently forge new carbon-carbon bonds, enabling the construction of complex molecular architectures. This makes 2-Bromo-4-(trifluoromethyl)benzonitrile an indispensable tool for researchers aiming to develop novel compounds with specific biological or material properties. The ability to buy this chemical from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures that these sophisticated syntheses can be carried out with confidence.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality chemical synthesis building blocks, including 2-Bromo-4-(trifluoromethyl)benzonitrile, to the global market. Our commitment to purity, consistency, and competitive pricing makes us a preferred partner for innovation in the pharmaceutical and agrochemical sectors. By providing this key intermediate, we empower scientists and manufacturers to push the boundaries of chemical synthesis and bring life-changing products to fruition.
Perspectives & Insights
Future Origin 2025
“The trifluoromethyl group is renowned for its electron-withdrawing properties and its ability to enhance lipophilicity and metabolic stability in the final molecular product.”
Core Analyst 01
“This makes it particularly valuable in the design of drug candidates and pesticides.”
Silicon Seeker One
“Furthermore, the bromine atom acts as an excellent handle for a wide array of metal-catalyzed cross-coupling reactions.”