Key Intermediate: Applications of 2-Chloro-3,6-difluorobenzaldehyde in Synthesis
The realm of organic synthesis is constantly seeking novel building blocks that can enable the efficient creation of complex molecular architectures. 2-Chloro-3,6-difluorobenzaldehyde (CAS: 261762-39-4) has emerged as a particularly valuable intermediate due to its trifunctional nature: an aldehyde group and two distinct halogen substituents on an aromatic ring. This unique combination grants it considerable versatility in a wide range of synthetic strategies.
In the pharmaceutical industry, 2-Chloro-3,6-difluorobenzaldehyde is a sought-after precursor for synthesizing Active Pharmaceutical Ingredients (APIs). The fluorine atoms can enhance metabolic stability, improve cell membrane permeability, and alter binding affinities to biological targets, all crucial factors in drug design. The aldehyde group readily participates in reactions like Wittig olefination, reductive amination, and cyclization reactions, essential for constructing heterocyclic systems common in many drug candidates. Researchers looking to buy this compound for drug discovery will appreciate its potential in creating novel scaffolds.
Similarly, in the agrochemical sector, this fluorinated benzaldehyde derivative serves as a key intermediate for developing new herbicides, insecticides, and fungicides. The incorporation of fluorine can impart enhanced bioactivity, environmental persistence, or selective toxicity to target pests. The ability to functionalize this molecule further allows for fine-tuning of its agrochemical properties.
For manufacturers and suppliers, providing high-purity 2-Chloro-3,6-difluorobenzaldehyde, often specified at ≥99.0% purity, is paramount. Companies seeking this intermediate can find reliable sources from manufacturers in China. Understanding the current price and availability from a trusted supplier is crucial for planning synthesis campaigns and ensuring project continuity. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of such critical chemical intermediates, committed to supporting advancements in scientific research and chemical manufacturing.
Perspectives & Insights
Agile Reader One
“2-Chloro-3,6-difluorobenzaldehyde (CAS: 261762-39-4) has emerged as a particularly valuable intermediate due to its trifunctional nature: an aldehyde group and two distinct halogen substituents on an aromatic ring.”
Logic Vision Labs
“This unique combination grants it considerable versatility in a wide range of synthetic strategies.”
Molecule Origin 88
“In the pharmaceutical industry, 2-Chloro-3,6-difluorobenzaldehyde is a sought-after precursor for synthesizing Active Pharmaceutical Ingredients (APIs).”