In the realm of organic chemistry, the selection of appropriate building blocks and intermediates is critical for achieving efficient and successful synthesis pathways. 1,2,5,8-Tetrahydroxyanthraquinone (CAS 81-61-8), a distinctive anthraquinone derivative, stands out as a valuable fine chemical intermediate with diverse applications in synthesis. Understanding its properties and how to procure it effectively is essential for chemists and procurement professionals alike.

What is 1,2,5,8-Tetrahydroxyanthraquinone?

1,2,5,8-Tetrahydroxyanthraquinone, also known by its common name Quinalizarin, is an organic compound characterized by its molecular formula C14H8O6. It typically appears as a white to off-white powder. Its structure features an anthraquinone core decorated with four hydroxyl groups, which impart specific chemical reactivities and physical properties. This compound serves primarily as an intermediate in various organic synthesis routes and is also recognized for its utility in pharmaceutical intermediate development.

Key Properties and Benefits for Synthesis:

  • Chemical Reactivity: The presence of hydroxyl groups and the anthraquinone backbone provides multiple sites for chemical modification. This allows chemists to use 1,2,5,8-Tetrahydroxyanthraquinone as a versatile starting material for creating more complex organic molecules.
  • High Purity Availability: For critical synthesis applications, consistent purity is non-negotiable. Reputable manufacturers offer 1,2,5,8-Tetrahydroxyanthraquinone with purity levels typically at 98% or higher. Sourcing high-purity material ensures predictable reaction outcomes and minimizes the need for extensive purification steps.
  • API Intermediate Potential: Its chemical structure makes it a promising intermediate for the synthesis of Active Pharmaceutical Ingredients (APIs). Researchers in the pharmaceutical sector can leverage this compound to build drug candidates with specific biological activities.
  • Established Synthesis Routes: As a recognized fine chemical, there are established methods for its use in various synthetic transformations, making it an accessible building block for both academic research and industrial applications.

Where to Buy 1,2,5,8-Tetrahydroxyanthraquinone

Procuring this essential chemical intermediate requires careful consideration of suppliers. Manufacturers based in China are often primary sources, offering competitive pricing and large-scale production capabilities for businesses needing to buy CAS 81-61-8 in bulk. When looking for a supplier, focus on those that provide detailed specifications, certificates of analysis, and have a demonstrated history of reliability in supplying fine chemicals for organic synthesis.

For R&D laboratories or smaller-scale projects, specialized chemical distributors can also be a good option. However, for consistent, high-volume needs, establishing a direct relationship with a manufacturer ensures better control over quality, pricing, and delivery schedules.

The Strategic Importance of Intermediates

The efficiency and success of any complex organic synthesis project are heavily reliant on the quality and availability of its intermediates. 1,2,5,8-Tetrahydroxyanthraquinone exemplifies this, offering chemists a robust platform for molecular construction. By understanding its characteristics and strategically sourcing it from reliable manufacturers and suppliers, organizations can significantly enhance their synthetic capabilities and drive innovation in chemical and pharmaceutical development.