In the dynamic field of organic chemistry, specific building blocks are essential for synthesizing novel compounds with diverse applications. Among these, 3-Bromobenzotrifluoride (CAS 401-78-5) stands out as a highly valuable intermediate. Its unique structure, featuring a trifluoromethyl group and a bromine atom on a benzene ring, imparts specific reactivity and properties that are leveraged extensively by research scientists and product formulators. This article delves into the significance of 3-Bromobenzotrifluoride in modern organic synthesis and highlights why sourcing it from a reliable manufacturer is crucial.

Chemical Properties and Reactivity of 3-Bromobenzotrifluoride

3-Bromobenzotrifluoride, a clear liquid, possesses a boiling point of approximately 151-152°C and a density of 1.61 g/mL at 25°C. The presence of the electron-withdrawing trifluoromethyl group influences the reactivity of the aromatic ring and the bromine atom. This makes it an excellent substrate for various palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. These reactions are cornerstones of modern synthetic chemistry, enabling the efficient formation of carbon-carbon bonds, which is vital for constructing complex molecular architectures.

Applications in Key Industries

The versatility of 3-Bromobenzotrifluoride makes it a sought-after intermediate in several high-value industries. In the pharmaceutical sector, it serves as a critical building block for synthesizing active pharmaceutical ingredients (APIs). The trifluoromethyl group is often incorporated into drug molecules to enhance metabolic stability, lipophilicity, and binding affinity. Researchers looking to buy 3-Bromobenzotrifluoride for drug discovery projects can rely on its predictable reactivity. Similarly, in the agrochemical industry, this compound is used to develop new pesticides and herbicides, where the trifluoromethyl moiety can improve efficacy and persistence. The demand for this chemical underscores the need for consistent supply from dependable manufacturers.

Sourcing and Supplier Considerations

For businesses aiming to purchase 3-Bromobenzotrifluoride, selecting the right supplier is paramount. A reputable manufacturer, such as those based in China, can offer high-purity material at competitive prices. When inquiring about price for 3-Bromobenzotrifluoride, it's important to consider factors beyond the unit cost, including batch-to-batch consistency, lead times, and the supplier's adherence to quality standards. Understanding the product's CAS number, 401-78-5, ensures you are sourcing the correct material. We, as a dedicated supplier, provide detailed specifications and support for all your inquiries.

Furthermore, the logistical aspects of obtaining this chemical, including packaging and transportation, are managed with care by experienced suppliers. Whether you need research quantities or bulk supply, ensuring your supplier can handle these demands effectively is key.

In summary, 3-Bromobenzotrifluoride (CAS 401-78-5) is an indispensable reagent in modern organic synthesis, powering innovation in pharmaceuticals, agrochemicals, and beyond. As a leading manufacturer and supplier, we are committed to providing researchers and industrial clients with the highest quality material. Contact us to discuss your specific needs and to secure your supply of this critical fine chemical intermediate.