For professionals in the chemical and pharmaceutical industries, sourcing high-quality intermediates is paramount to successful R&D and production. One such crucial compound is 3-chloro-1,1,1-trifluoropropan-2-one, identified by its CAS number 431-37-8. This halogenated ketone is a versatile building block, particularly valued for its trifluoromethyl group, which imparts unique properties to the molecules it helps create. If you are a procurement manager or a research scientist looking to procure this essential chemical, understanding its attributes and the global supply landscape is key.

Understanding 3-Chloro-1,1,1-trifluoropropan-2-one (CAS 431-37-8)

This compound, also known by synonyms such as 1-chloro-3,3,3-trifluoroacetone, typically presents as a clear liquid. Its chemical formula is C3H2ClF3O, with a molecular weight of approximately 146.50 g/mol. Key physical properties often cited include a boiling point around 71-72°C and a density of about 1.422 g/cm³. The purity is generally specified as a minimum of 95%, which is critical for applications where precision and absence of impurities are non-negotiable, such as in pharmaceutical synthesis. Its reactivity stems from both the electrophilic carbonyl group and the presence of the chlorine atom, making it an excellent participant in various organic reactions.

Applications in Chemical Synthesis

The primary utility of 3-chloro-1,1,1-trifluoropropan-2-one lies in its role as an intermediate. Researchers and formulators leverage its structure to introduce the trifluoromethyl group into complex organic molecules. This group can significantly influence a molecule's lipophilicity, metabolic stability, and binding affinity, making it highly desirable in drug discovery and the development of advanced agrochemicals. As a manufacturer, we see consistent demand from sectors focused on novel pharmaceutical intermediates and specialized organic compounds.

Sourcing Strategies for Procurement Managers

When looking to buy 3-chloro-1,1,1-trifluoropropan-2-one, procurement managers should prioritize suppliers who offer reliability, consistent quality, and competitive pricing. Identifying a reputable 3-chloro-1,1,1-trifluoropropan-2-one manufacturer in China can provide significant advantages. These advantages often include cost-effectiveness due to production scale and efficient supply chain management. It is advisable to request samples and Certificates of Analysis (CoA) to verify purity and specifications before placing bulk orders.

Why Choose NINGBO INNO PHARMCHEM CO.,LTD. as Your Supplier?

At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to meeting the stringent demands of the chemical industry. We are a leading manufacturer and supplier of organic synthesis intermediates like 3-chloro-1,1,1-trifluoropropan-2-one. Our commitment is to provide you with a high-quality product at a competitive price, backed by robust quality control and efficient logistics from China. We understand the importance of timely delivery and product consistency for your research and manufacturing processes. If you are seeking a dependable source for CAS 431-37-8, we invite you to contact us for a quote and sample. Secure your supply chain with a trusted partner.