In the pharmaceutical industry, the selection of excipients is as critical as the active pharmaceutical ingredients (APIs) themselves. Excipients ensure drug stability, enhance bioavailability, and improve patient compliance. Sorbitan Monooleate, commonly known as Span 80 (CAS 1338-43-8), is a versatile nonionic surfactant and emulsifier that plays a significant role in various pharmaceutical formulations. NINGBO INNO PHARMCHEM CO.,LTD., a reputable chemical manufacturer and supplier in China, is dedicated to providing high-quality pharmaceutical-grade ingredients to meet the stringent demands of the sector.

The Pharmaceutical Utility of Span 80

Span 80 is a sorbitan ester characterized by its low HLB value (around 4.3), making it an excellent choice for creating stable water-in-oil (W/O) emulsions. Its properties as a lipophilic emulsifier, wetting agent, and dispersant are invaluable in pharmaceutical applications:

  • Emulsifier in Topical Formulations: Span 80 is extensively used in creams, ointments, and lotions to create stable W/O emulsions. This is vital for delivering lipophilic APIs effectively to the skin, ensuring consistent dosing and absorption.
  • Wetting and Dispersing Agent: It acts as a wetting agent for poorly soluble drugs and as a dispersant for active ingredients like zinc oxide, calamine, and certain antibiotics in lipophilic pharmaceutical bases, ensuring uniform distribution and preventing aggregation.
  • Stabilizer for Drug Delivery Systems: Its ability to stabilize emulsions contributes to the overall shelf-life and integrity of various drug delivery systems.
  • Enhancing Bioavailability: By aiding in the dispersion and solubilization of lipophilic compounds, Span 80 can contribute to improved bioavailability of certain medications.
  • Combination with Hydrophilic Surfactants: Often used in conjunction with hydrophilic surfactants like Tweens, Span 80 helps form complex emulsion systems with tailored HLB values, expanding formulation possibilities.

Procuring High-Purity Span 80 from a Trusted Manufacturer

For pharmaceutical formulators and procurement managers, sourcing high-purity excipients is non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD. understands these requirements. We are a leading chemical supplier in China, committed to providing Span 80 that meets rigorous quality standards, including pharmacopoeial compliance where applicable. We ensure batch-to-batch consistency and a reliable supply chain, which is crucial for pharmaceutical manufacturing. If you are looking to buy Span 80 for your pharmaceutical needs, consider us for competitive pricing and dependable delivery.

Partner with Us for Your Pharmaceutical Excipient Needs

Choosing NINGBO INNO PHARMCHEM CO.,LTD. means partnering with a chemical manufacturer that values quality, reliability, and customer satisfaction. Our sorbitan monooleate is ideal for drug development and manufacturing. Contact us today to learn more about our product specifications, request a sample, and inquire about our bulk purchase options. Secure your supply of this essential pharmaceutical excipient from a trusted source.