The Synthesis and Properties of 3,5-Dinitrobenzoic Acid: A Chemical Overview
For chemists and material scientists, understanding the synthesis and properties of key chemical compounds is fundamental to their effective utilization. 3,5-Dinitrobenzoic Acid (CAS 99-34-3) is a compound that warrants such attention due to its diverse applications. This article provides a chemical overview, discussing its synthesis pathways and characterizing its essential physical and chemical properties, from a trusted supplier perspective at NINGBO INNO PHARMCHEM CO.,LTD.
### Synthesis Routes to 3,5-Dinitrobenzoic Acid
The production of 3,5-Dinitrobenzoic Acid typically involves the nitration of benzoic acid or its derivatives. A common method involves treating benzoic acid with a mixture of concentrated nitric acid and sulfuric acid. The reaction conditions, such as temperature and reaction time, are carefully controlled to promote the desired dinitration at the meta positions. Benzoic acid, under these strongly acidic and oxidizing conditions, undergoes electrophilic aromatic substitution where the nitro groups are introduced onto the benzene ring. The presence of the carboxyl group on benzoic acid acts as a meta-director, guiding the nitro groups to the 3 and 5 positions.
Another synthetic approach can start from 3-nitrobenzoic acid, which is then subjected to a second nitration step. The efficiency of these synthesis methods is crucial for industrial production. Factors such as yield, purity of the product, and the environmental impact of the process are all considered when optimizing production strategies. Researchers often look for high-yield synthesis pathways to ensure cost-effectiveness when they need to buy 3,5-Dinitrobenzoic Acid for their projects.
### Key Physical and Chemical Properties
3,5-Dinitrobenzoic Acid typically appears as an off-white to slightly yellow crystalline powder. Its melting point is consistently reported in the range of 204-206 °C, indicating a stable solid form at room temperature. The molecule's structure, C7H4N2O6, with a molecular weight of 212.12 g/mol, features two strongly electron-withdrawing nitro groups. These groups significantly increase the acidity of the carboxylic acid proton compared to benzoic acid itself. Its pKa value is around 2.82, making it a stronger acid than benzoic acid.
In terms of solubility, 3,5-Dinitrobenzoic Acid is generally insoluble in water but soluble in organic solvents like ethanol and glacial acetic acid. Its stability is good when stored properly in tight containers, away from light, in a cool, dry, and well-ventilated area. Understanding these properties is essential for handling, storage, and formulating the compound for its intended applications.
### Your Reliable Source for Chemical Insights
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing not only high-quality chemicals like 3,5-Dinitrobenzoic Acid but also valuable information about their synthesis and properties. As a leading supplier and manufacturer in China, we understand the importance of detailed product knowledge for our clients. When you choose to buy 3,5-Dinitrobenzoic Acid from us, you are partnering with a company that values scientific understanding and reliable supply, ensuring your research and production efforts are well-supported.
### Synthesis Routes to 3,5-Dinitrobenzoic Acid
The production of 3,5-Dinitrobenzoic Acid typically involves the nitration of benzoic acid or its derivatives. A common method involves treating benzoic acid with a mixture of concentrated nitric acid and sulfuric acid. The reaction conditions, such as temperature and reaction time, are carefully controlled to promote the desired dinitration at the meta positions. Benzoic acid, under these strongly acidic and oxidizing conditions, undergoes electrophilic aromatic substitution where the nitro groups are introduced onto the benzene ring. The presence of the carboxyl group on benzoic acid acts as a meta-director, guiding the nitro groups to the 3 and 5 positions.
Another synthetic approach can start from 3-nitrobenzoic acid, which is then subjected to a second nitration step. The efficiency of these synthesis methods is crucial for industrial production. Factors such as yield, purity of the product, and the environmental impact of the process are all considered when optimizing production strategies. Researchers often look for high-yield synthesis pathways to ensure cost-effectiveness when they need to buy 3,5-Dinitrobenzoic Acid for their projects.
### Key Physical and Chemical Properties
3,5-Dinitrobenzoic Acid typically appears as an off-white to slightly yellow crystalline powder. Its melting point is consistently reported in the range of 204-206 °C, indicating a stable solid form at room temperature. The molecule's structure, C7H4N2O6, with a molecular weight of 212.12 g/mol, features two strongly electron-withdrawing nitro groups. These groups significantly increase the acidity of the carboxylic acid proton compared to benzoic acid itself. Its pKa value is around 2.82, making it a stronger acid than benzoic acid.
In terms of solubility, 3,5-Dinitrobenzoic Acid is generally insoluble in water but soluble in organic solvents like ethanol and glacial acetic acid. Its stability is good when stored properly in tight containers, away from light, in a cool, dry, and well-ventilated area. Understanding these properties is essential for handling, storage, and formulating the compound for its intended applications.
### Your Reliable Source for Chemical Insights
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing not only high-quality chemicals like 3,5-Dinitrobenzoic Acid but also valuable information about their synthesis and properties. As a leading supplier and manufacturer in China, we understand the importance of detailed product knowledge for our clients. When you choose to buy 3,5-Dinitrobenzoic Acid from us, you are partnering with a company that values scientific understanding and reliable supply, ensuring your research and production efforts are well-supported.
Perspectives & Insights
Molecule Vision 7
“Its stability is good when stored properly in tight containers, away from light, in a cool, dry, and well-ventilated area.”
Alpha Origin 24
“Understanding these properties is essential for handling, storage, and formulating the compound for its intended applications.”
Future Analyst X
“is committed to providing not only high-quality chemicals like 3,5-Dinitrobenzoic Acid but also valuable information about their synthesis and properties.”