For professionals engaged in chemical synthesis, understanding the properties and applications of key reagents is vital for successful product development and research. 6-Carboxytetramethylrhodamine, identified by CAS number 91809-67-5, is a rhodamine derivative that holds significant importance as a fluorescent labeling agent. As a specialized chemical manufacturer and supplier, we aim to provide clarity on this compound, its utility in synthesis, and the advantages of sourcing it from a reputable provider.

6-Carboxytetramethylrhodamine is a fluorescent dye characterized by its vibrant emission in the orange-red region of the spectrum. Its molecular structure includes a reactive carboxylic acid group, which is a critical feature for its application in chemical synthesis, particularly in bioconjugation. This functional group allows for covalent attachment to amines, hydroxyls, or thiols (after appropriate activation), enabling the creation of labeled peptides, proteins, nucleotides, and other biomolecules. The compound’s inherent fluorescence makes these conjugates readily detectable and quantifiable.

In the context of chemical synthesis, the purity of reagents is paramount. Our 6-Carboxytetramethylrhodamine is produced under strict quality control measures, ensuring high assay purity (often ≥95%). This high purity is essential for achieving predictable reaction outcomes and for applications where minimal background fluorescence or side reactions are critical. We understand that researchers and synthesis chemists need reliable raw materials, which is why we are a trusted supplier in China, offering consistent quality and competitive pricing for this valuable reagent.

The synthesis of conjugates using 6-Carboxytetramethylrhodamine typically involves activating the carboxylic acid group to form a reactive ester or another activated species. This activated form then readily reacts with nucleophilic sites on the target molecule. Common applications include labeling amino acids for peptide synthesis, modifying antibodies for immunodiagnostics, or preparing probes for molecular biology techniques. When you purchase this reagent, it’s important to consider the availability of technical data sheets and potential conjugation protocols from your supplier.

For organizations looking to buy CAS 91809-67-5 in bulk for synthesis projects, partnering with an experienced manufacturer is crucial. We offer the capacity to supply significant quantities while maintaining our commitment to quality and timely delivery. Our aim is to simplify the procurement process, allowing synthesis chemists and project managers to focus on their core R&D objectives without compromising on the quality of their starting materials.

In summary, 6-Carboxytetramethylrhodamine (CAS 91809-67-5) is a versatile and highly valuable reagent for chemical synthesis, particularly for creating fluorescently labeled biomolecules. As a dedicated supplier, we are committed to providing R&D professionals with the high-purity compound they need, backed by excellent service and competitive pricing. Contact us to discuss your synthesis requirements and secure your supply of this essential fluorescent dye.