Acetophenone, identified by its CAS number 98-86-2, is a fundamental organic compound within the chemical industry, recognized as the simplest aromatic ketone. Its structure, comprising a phenyl group directly bonded to an acetyl group (CH3CO-), lends it a unique combination of properties that are leveraged across a multitude of applications. From its characteristic odor to its reactivity as a solvent and synthetic intermediate, Acetophenone is a cornerstone chemical. This article aims to provide a comprehensive overview of its properties, production methods, and diverse uses, emphasizing the importance of sourcing from reliable manufacturers.

Physically, Acetophenone typically appears as a colorless to pale yellow liquid or crystalline solid, with a melting point around 19-20°C and a boiling point of approximately 202°C. Its most notable sensory characteristic is its sweet, floral, and somewhat pungent aroma, often compared to hawthorn or orange blossoms. This olfactory profile makes it a highly valued ingredient in the fragrance and flavor industries, where it is used to impart pleasant scents to perfumes, soaps, detergents, and various food products. Companies seeking to buy Acetophenone for these applications will prioritize its sensory qualities and purity.

Chemically, Acetophenone exhibits the reactivity typical of ketones, including addition reactions at the carbonyl group and electrophilic substitution on the aromatic ring. It is moderately soluble in water but readily dissolves in most organic solvents, such as ethanol, ether, and chloroform, making it a versatile solvent itself for certain resins and cellulose derivatives. Its stability under normal conditions, coupled with its specific reactivity, makes it a valuable reagent in organic synthesis. For instance, it can be hydrogenated to form 1-phenylethanol or further reacted to produce various derivatives used in pharmaceuticals and other fine chemicals.

The production of Acetophenone predominantly follows two main routes. The Friedel-Crafts acylation of benzene using acetyl chloride or acetic anhydride in the presence of a Lewis acid catalyst like aluminum chloride is a common laboratory and industrial method. Alternatively, it can be obtained as a significant byproduct during the Hock process, which involves the oxidation of ethylbenzene or cumene for phenol and acetone production. Understanding these production pathways is beneficial for buyers looking to assess supply stability and potential cost factors when they decide to purchase Acetophenone from manufacturers.

The applications of Acetophenone are remarkably diverse. In the pharmaceutical industry, it serves as a precursor for synthesizing various drug compounds. Its solvent properties are utilized in coatings and ink formulations. Its fragrance and flavor contributions are invaluable to the consumer goods sector. Furthermore, it acts as a polymerization catalyst in certain industrial processes. For businesses requiring Acetophenone, identifying a reputable supplier, particularly a manufacturer based in China known for quality and competitive pricing, is crucial for consistent and cost-effective procurement.